The maximum I have ever taken at once of d-ribose is 7.5 mg and I have not had it make me hypoglycemic. I have been taking it for over a year. I also eat ketogenic and take 2500 mg of metformin per day. Also, you and Gretchen must have guts of steel if you can take 10-15 mg at once without having diarrhea! I have to take it just after a meal for that same reason.

Where did you read that it is made from corn? Are you buying some with added maltodextrin, or did you read that the d-ribose itself is made from corn?

 

I have taken 30 gms in a day......no issues.

 

Yes, I'm sure this is some major clue that others, like Gretchen, tolerate 20g well, and I don't.

I wasn't saying last week that it was raising blood sugar, but that it made my head feel woozy like I had too much sugar. When I had that feeling in the past, I always assumed it was increased blood sugar, but then I started testing and realized it wasn't. That's what made me test last night. I wanted to prove to myself that it wasn't raised, and indeed, it was shockingly low.

I'm not sure that my EMF issues are worse than Gretchen's, however, we all respond differently to unnatural stressors. I think that how I respond negatively to EMF vs how she responds (like the migraines) will tell us something, somehow about our issues.

 

I'll assume you mean gm. Slip of fingers!

Diarrhea hasn't been an issue with d-ribose for me at all.

Just one example of the corn issue when I google "d-ribose corn": http://www.livestrong.com/article/496655-d-ribose-safety/

Some interesting discussion: http://www.prohealth.com/me-cfs/blog/boardDetail.cfm?id=1331573
vickiw is another person who gets hypoglycemia from it (comment a little less than halfway down).
Cherylsue says: Dr. Cheney talked about it in his DVD. It failed in about a third of his patients because they couldn't metabolize the extra carbon molecule in that particular sugar and D-Ribose became toxic to them. ( I can't handle it myself. I feel terrible on it.)

However, if you don't have that deficiency, it may work. You would have to try it to see.

I just noticed that m y d-ribose (NOW brand) has a long list of things it is free of, but it does not say "corn-free." :headdesk:

 

Cheney, and Dr Myhill (in the UK) are two research & clinical doctors who have looked extensively at d-ribose for ME/CFS. Neither of them suggest it's a supplement for everyone. I wonder what the deficiency is that Cheney refers to there?
Might be useful to know for those here who can't tolerate it?

 

I'm not going to be any help here, but your post made me wonder about d-ribose effect on BG. I took 5 g at 2 pm (6 hours after breakfast). Initial BG was 110 (normal for me), 104 at 1 hour and 100 at 2 hours. Maybe there would be a larger effect if I took more, but that is my usual dose, twice per day.

 

5gm doesn't seem to give me any hypoglycemic effect.

freesia, that same link discusses Dr. Myhill, IIRC. I also turned up a google link where she said most (or all?) d-rib was made from corn, but when I clicked on it, the link didn't work.

 

Yes, I meant "g" and not "mg." My fingers do not always type what my brain is thinking, haha! Thanks for the link to the discussion about corn. So far, d-ribose has been a lifesaver for me in terms of energy, fibromyalgia-type symptoms, and arrhythmia, and with just the 5-7.5 g per dose max that I have been using 3-4 times per day for the past year, it has never given me bothersome hypoglycemia.

 

I can take 10gm in my morning coffee and I am fine. The minute I up it to 15gm, with no other food or supp changes I get this nervous butterfly like feeling in my stomach. I dropped back down to 10gm and I am just fine. Not sure what's going on there but 10 is perfect for me! I haven't tested the blood sugar issue so not sure how it reacts with that.

 

Kathylu

earlier in this thread and in the Mitochondrial RX Jack has said d-ribose will lower bg across the board. Which if you look a MamaG's experience - it drops her BG like a stone - so she's more responsive to it from that case - the question is - what's not working for her - that d-ribose not only is dropping her BG, but also impacting her binging. So where's her disconnect? I think that's what she's trying to figure out... I don't have any answers for her... just my n=1...which isn't helpful for her at all...

ETA: I'm taking LEF D-ribose ingredients say NON-GMO D-ribose.

 

MG, I'm not talking about you behind your back! Just my opinion, but if you are having that intense a reaction to d-ribose, you should consider only taking it with food, or not at all. If your BG drops to 49 (!!!) after 10 grams of ribose, I'm not surprised you would be a trembling, dizzy, hungry, craving maniac. Low blood sugar does exactly this to you...signals you to EAT NOW.

You should probably assess the cost/benefit ratio of d-ribose. You may not need it anyway. Also, if sugar cravings are a known problem for you, I would think the yummy, sugary taste of d-ribose could certainly set those cravings into high gear again.

 

Yes, 5gm 3x/day does work fine for me, but 10 is too much, and I can't stop at 5. Gar!

I haven't seen any benefit from it yet, but I was hoping to. I will just stick with all the other mito rx stuff for now, and keep d-rib in mind for a future when I don't have any risk of cravings getting out of control again.

 

I did not have any reaction after meals either. My problem was that my FBG started going up to 105 after months of being normal.

 

MG - if you are taking all the mito Rx supps, be aware that alpha lipoic acid can also lower your blood glucose, so by combining with d-ribose, the effect may be compounded. http://www.livestrong.com/article/503438-side-effects-of-alpha-lipoic-acid-and-acetyl-l-carnitine/. My FBG has dropped from mid-80s to 68.

 

I'm up to 20-30g per day. I take 10g in my coffee (2cups) and 10g in my mineral water with stevia. No upset stomach. Could it be the other foods you are consuming in addition to the D-ribose that may need more investigation.

 

Just wanted to mention that NOW brand d ribose is non GMO as well. I emailed the company and got this response.


We sell the branded ingredient “Bioenergy d-Ribose, which has a non-GMO certificate, so you’re safe with ours.
http://www.bioenergyribose.com/the-advantage

It's much cheaper then LEF and tastes the same.

 

Quite a few foods contain riboflavin (B2). That's ribose + flavin.

If someone perceives a negative experience with d-ribose couldn't they supplement with larger doses of reduced riboflavin?

 

GlenPDQ, I'm not sure you could consider my experience "perceiving," since I measured it with a glucose meter, but you raise an interesting question about a possible connection between B2 & the effects of d-rib.

So far I've spent 2 weeks adding each new supp so I can see any isolated positive or negative or cumulative effects. I've only added the three Mg's & the D-rib so far.

The foods are the same I always have - pastured pork sausage, grassfed ground beef, wild sockeye salmon (& other wild fish, same as always), coconut oil, lard. Same amounts, same times.

Of course, I'm not having an upset stomach at all, just the plummeting blood sugar and the symptoms that go with that (woozy, weak, shaky, etc.).

 

I have finally taken the next step to try d-ribose. I have to report this stuff does amazing things to demolish my hunger. I have been taking only 5 grams of Pure Encapsilations with my BAB (as it says to take with food) for a few weeks and what I have noticed is I am stuffed after eating what I normally would for lunch and I am not hungry until 6:30 ish and that is just a reminder that I should eat. I can eat only a little bit and be completely satisfied. It is not this blaring, go crazy if I don't eat which is what I have experienced for a long time. I now look at food like "meh" as some would say. I am pretty happy with this stuff. I don't know if it is doing anything else but I sure like what it is doing that I have noticed.

 

D-ribose will uncover some amazing things that are happening across one's brainstem.......what it reveals may not be perceptible to the person it is happening to but when you marry the observation with the phenotype it begins to open a door to what really might the issue.