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What the H--- is Factor X??? Post your guesses.

Discussion in 'Cold Thermogenesis' started by AKMan, Mar 14, 2012.

  1. AKMan

    AKMan New Member

    I think Factor X is Brown Adipose Tissue.
  2. RiverNeighbor

    RiverNeighbor New Member

    I think it's something related to dna methylation and related proteins/enzymes.....

    P.S. Love this topic... I love to guess about what's under the wrapping paper.
  3. Melinda

    Melinda New Member

    I was just looking at pictures of our ancestors, mulling this question over. Besides the huge increase in brain real-estate, the nose became more prominent and the jaws shrank. I'm going with Factor X having something to do with our sense of smell connection to the brain that helps the creation of memories for better thinking and reasoning and needing more brain real-estate. When my kids reached the age of reason, smells that they used to ignore became more noticeable to them. As I'm aging, my once acute sense of smell seems dull.
  4. Valorie33

    Valorie33 New Member

    Maybe Altitude.........
  5. Birdy

    Birdy New Member

    Something ionic, like grounding. Think sitting in a bare cafe, on top of a mountain, or in a real pool of water or ocean.
  6. LinD

    LinD New Member

    Is Factor-X something that occurs as a result of A + B + C?
  7. Lexi

    Lexi New Member

    freeze + squeeze + breathe = factor x (or the "tourniquet effect")
  8. Souldanzer

    Souldanzer Banned

    Doubt it's Factor X, though....
  9. jenn

    jenn New Member

    My guess is that Factor X has something to do with reduced oxygen during sleep, (our daily "hibernation") especially when combined with cold. My reasoning is that many species, even mammals, consume little to no oxygen during hibernation and emerge in spring healthy and with no apparent damage. With proper conditioning I think it's possible that humans could do this (some freedivers can survive underwater on greatly reduced oxygen for long periods of timed), but as a non-scientist I am unwilling to speculate on the potential benefits. Feel free to pipe up and tell me what you think!
  10. Souldanzer

    Souldanzer Banned

    and maybe more likely :)

    if it turns out to be kundalini yoga in the freezing bathtub - that's it for me :eek: no more!!
  11. Groketteliveson

    Groketteliveson New Member

    I say it's the power of positive thinking...
  12. Continuum Fitness

    Continuum Fitness New Member

    I was thinking this myself. Constriction or compression. Notice the company Dr. refers to uses compression cuffs to make the body produce lactic acid quicker. Also I have read somewhere Navy Seals use isometric muscle contractions when in cold situations to make their body increase body heat.
  13. Birdy

    Birdy New Member

    Hey, I'm going to vote again. I think the good doctor truly is a lunatic. ;)
  14. Groketteliveson

    Groketteliveson New Member

    Or meditation of some sort.
  15. Kirstin

    Kirstin New Member

    me, too! Methylation and cell membrane permeability.
  16. Souldanzer

    Souldanzer Banned

    Kundalini Yoga sort of covers all of that... not happy.

    And I just read that hypoxia up regulates eNOS expression :( I'm not holding my breath, sorry. I'll climb a mountain but I won't hold my breath. Not happening.
  17. hellojtm

    hellojtm New Member

    Well I like this path, but I'm pretty sure that Factor X is going to be the reason for evolving a warm adapted metabolism. He is saying that the cold adapted metabolism is the ancient pathway. So what change in hominid evolution warranted the selective pressure to develop an entire metabolism to optimize for it? I.e. we need to be looking at causes for the warm adapted in early early hominids, not another piece to the holy trinity of optimal...

    So, let's put them together. Due to *something* environmental, early hominids found a route in which they could rapidly produce epigenetic changes and this allowed them to prosper in the warm adapted environment, but it's at the cost of stem cells and telomere lengths due to the "hunting" and "searching" that the epigenetic changes require to find an optimal state. So then you cycle back in winter to the good old cold adapted state which lengthens the telomeres and produces autophagy to clean up the mess from summer.

  18. Amy

    Amy Silver

    I think that it is hypoxia -- not pathological hypoxia as described in the quilt but rather a lower oxygen level that the body has accomadated to. Dr. k even briefly referenced survivability with a paO 2 of 35. ("normal" being typically above 95 at sea level). Of course Sherpas live at great altitude and experience and accommodate to lower oxygen levels. Many elite athletes train at altitude and many also effectively sleep at altitude by purchasing hypoxicator sleeping tents.... So , you're in the cold, dark and low oxygen---almost sounds like suspended animation...
  19. Souldanzer

    Souldanzer Banned

    not sure it's Factor X (still thinking Factor X might be the sum of A+B+C) but I fear hypoxia will still play a role... somewhere...
  20. Susan M.

    Susan M. New Member

    I can't hold my breath very long at all, that is why I am in the tub and not still holding my breath for a face dunk!

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