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Sue-UK Journal 2018/19/20/22/23

Discussion in 'My Optimal Journal' started by Sue-UK, May 26, 2018.

  1. Pablo

    Pablo New Member

    When I saw the video I was like... hughh classical music. My mind in the beggining didn´t want to listen ("boooring :zzz:"). I tend to avoid classical music quite a lot. Why so many people avoid it, especially the youngest? I stopped, closed my eyes, an listened. After 10 seconds I began enjoying it and at minute 1 or 2 I had tears in my eyes, I really loved it by the end.

    Is it cause this kind of music requires a certain mental and/or emotional state to really appreciate, that you cannot appreciate being mindless, distracted, etc?? That you need to be really still, relaxed? I may begin to add a bit of this... "classical music meditation".

    Is it being able to appreciate broader kinds of music a reflection of a person being able tu tune into different kinds of emotions, without hiding from them? Hmmm
     
  2. Pablo

    Pablo New Member



    One of the few classical (I think it is classical, don´t know much about music) tracks I listen a lot (I bought my parents some Zimmer CD´s)

    Maybe I need to listen to more "boring" music (e.g. slower, classical ), to tune into some different feelings. Hmmm...
     
  3. Sue-UK

    Sue-UK New Member

    2cellos "The Trooper Overture" is a "mash-up of Rossini’s ‘William Tell Overture’ with rock legends Iron Maiden‘s ‘The Trooper’."

    Worth watching right through …. Think I should buy shares in a company making cello bow strings …:D

     
    Last edited: Mar 7, 2020
    Alex97232 and Pablo like this.
  4. Pablo

    Pablo New Member

    I don´t find words to describe theses guys, jesus. I´m so damm heterosexual, but I´m reconsidering. What fucking vibes... Stephan is hilarious... I´m addicted to these guys, is it "healthy dopamine"?

     
    Sue-UK likes this.
  5. Sue-UK

    Sue-UK New Member

    Alex97232 likes this.
  6. Sue-UK

    Sue-UK New Member

  7. Sue-UK

    Sue-UK New Member

    The spermidine rabbit hole :) Putting links in my old journal as I'm getting swamped ....

    From what I've read, endogenous production of spermidine decreases as a consequence of aging, so with its effect on autophagy, if the covid virus hijacks autophagy I'm at higher risk, being in a uk winter, even if I follow light water magnetism and get all the tech out etc. Some gut bacteria can produce it, or it can be increased via diet (aka blue zone diets) or as a last resort supplement, because they are normally extracted from wheatgerm and dosages are small.

    https://www.longevity.technology/spermidine-and-covid-19-supplements-for-improving-immune-health/
    https://www.scientificarchives.com/...tic-use-of-natural-compounds-against-covid-19

    http://www.aginganddisease.org/EN/10.14336/AD.2021.0603
    New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349183/
    New roles for autophagy and spermidine in T cells

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116155/
    Warmth Prevents Bone Loss Through the Gut Microbiota (change of species to those that produce spermadine)
     
  8. Sue-UK

    Sue-UK New Member

    https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(15)00468-4
    Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age

    https://aacrjournals.org/cancerres/...ermidine-Prolongs-Lifespan-and-Prevents-Liver
    Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy

    https://www.nature.com/articles/cdd... vivo,traumatic optic neuropathy and glaucoma.
    Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury

    https://link.springer.com/article/10.1007/s00726-021-03079-4
    Activation of whole body by high levels of polyamine intake in rats

    https://europepmc.org/article/MED/30306826
    Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?

    https://pubmed.ncbi.nlm.nih.gov/33496030/
    Spermidine promotes melanin production through an MITF signalling pathway
     
  9. Sue-UK

    Sue-UK New Member

  10. Sue-UK

    Sue-UK New Member

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432200/
    Polyamine Oxidase Is Involved in Spermidine Reduction of Transglutaminase Type 2-Catalyzed β H-Crystallins Polymerization in Calcium-Induced Experimental Cataract

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265913/
    Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004860/
    Protective Role of C-Phycocyanin Against Secondary Changes During Sodium Selenite Mediated Cataractogenesis
     
  11. Enhance your intermittent fasting in a Pill - Autophagy stimulated by spermidine -> fun
    Are you taking it as a pill https://spermidinelife.us/ or a shot of oil mixed with your salad?
     
    Last edited: Mar 4, 2022
  12. Sue-UK

    Sue-UK New Member

    No, the spermidine life supplement is expensive for 1 mg per dose, far better sources from diet. I've also found a chlorella being sold in the UK which has
    4.5 mg spermidine per 5g serving. :)
     
    John Schumacher likes this.
  13. Sue-UK

    Sue-UK New Member

    https://www.biorxiv.org/content/10.1101/2020.04.15.997254v1.full
    Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics
    "We observed elevated ATP levels that might facilitate energy-dependent processes such as virus replication and entry"

    Interested in that as heard on a podcast that spermidine is an uncoupler.
     
  14. Sue-UK

    Sue-UK New Member

    John Schumacher and Marko Pollo like this.
  15. Sue-UK

    Sue-UK New Member

     
    John Schumacher likes this.
  16. Sue-UK

    Sue-UK New Member

    Hypoxia 18 rabbit hole ... linked to my taking of spirulina.
    https://www.foodandnutritionjournal...19-response-option-early-evidence-of-promise/

    The studies I've looked at about the health benefits for various diseases seem to be about the nutrients, not about light absorbed or emitted by the ingested chlorophyll, or phycocyanin, i.e. whether is more about the light, a human version of capturing the photosynthetically active radiation done by plants...?

    https://arxiv.org/ftp/arxiv/papers/1012/1012.3371.pdf
    Emission of Mitochondrial Biophotons and their Effect on Electrical Activity of Membrane via Microtubules
    "Furthermore, MT polymerization is sensitive to UV [84] and blue light [59] and mitochondria are known to be sources of biophotons corresponding to the same wavelengths [8,34,98], which makes an immediate logical connection."

    https://iubmb.onlinelibrary.wiley.com/doi/epdf/10.1002/iub.359
    Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IR-A radiation
    "It has long been known that electronic excitation by light stimulates redox processes in organic dyes to intensify electron transfer (15). "

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885225/
    Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases

    https://www.mdpi.com/2072-6643/14/3/676

    Effect of Spirulina platensis crude extract on catalase activity and stability

    (pic from https://iopscience.iop.org/article/10.1088/1742-6596/1013/1/012205/pdf
    Characterization of phycocyanin from Spirulina fusiformis and its thermal stability)
    (Thinking of the "hot mitochondria" -Nick Lane)

    upload_2023-3-26_17-34-45.png
    Then
    [​IMG]

    Spirulina containing chlorophyll also goes back to https://journals.biologists.com/jcs.../Light-harvesting-chlorophyll-pigments-enable
    Light-harvesting chlorophyll pigments enable mammalian mitochondria to capture photonic energy and produce ATP

    Then its whether it can help someone to do human photosynthesis longer (making more vitamin D?) by protecting the skin .......

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017183/
    Phycocyanin Protects Against UVB-induced Apoptosis Through the PKC α/βII-Nrf-2/HO-1 Dependent Pathway in Human Primary Skin Cells
    (Don't understand the science :confused: but it kinda make sense as being a cyanabacteria it wouldn't have the same defences against excess uv as a plant would?)
     
    Last edited: Mar 27, 2023 at 3:54 AM
    JanSz likes this.

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