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probiotics for dry eyes

Discussion in 'Adrenal Rx and Leaky Gut Rx' started by chocolate, May 17, 2012.

  1. chocolate

    chocolate Silver


    Investigators diluted Lactobacillus acidophilus into a saline solution to create the eye-drop solution.

    Symptoms in all six patients who completed the study (one patient dropped out) were significantly improved at two weeks and four weeks. Clinical signs were also significantly better after four weeks (although not at the two-week mark). The impression cytology, which was performed in three patients, showed a down regulation of ICAM-1 and TLR-4 in two patients. “We were fairly surprised by the fact that every patient, regardless of statistically significant clinical improvement, described a positive effect of Lactobacilli eye drops on their symptoms, and none of them reported discomfort or the occurrence of side effects,â€￾ Dr. Iovieno said. He and fellow investigators are now analyzing the effects of prolonged oral consumption of Lactobacilli for more mild forms of eye allergies.

    A number of allergy studies, some of which also track eye symptoms, are finding good results associated with probiotic use. A review article published in the December 2008 issue of Annals of Allergy, Asthma, and Immunology analyzed 12 randomized controlled trials that studied the effects of probiotics in allergic rhinitis and asthma. “Nine of the 12 randomized controlled trails that evaluated clinical outcomes in allergic rhinitis showed an improvement due to the use of probiotics,â€￾ wrote lead investigator Harissios Vliagoftis, M.D., Department of Medicine, University of Alberta, Edmonton, Alberta. “All the [trials] that studied perennial allergic rhinitis showed lower symptom scoring with the use of probiotics compared with placebo. Also, five of the eight [trials] that referred to seasonal allergic rhinitis suggested an improvement in clinical outcomes,â€￾ he wrote. Four of the trials reviewed also tracked ocular allergy symptoms; all four of those studies reported decreased eye symptoms after probiotic use. Although Dr. Vliagoftis and co-investigators wrote that the mechanism of action for probiotics in allergy
    is not entirely clear, they may have an effect on immune regulation by altering the composition of gut flora. Others have postulated a connection to the so-called “hygiene hypothesis,â€￾ which is based on research that finds children exposed to more microbes earlier in life actually have a lower incidence of allergy and asthma than children who are exposed to fewer microbes.

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