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PBM and the gut.......

Discussion in 'Adrenal Rx and Leaky Gut Rx' started by Jack Kruse, Jan 3, 2022.

  1. Jack Kruse

    Jack Kruse Administrator

    The results suggested PBM alters the microbiome and thus it represents a therapeutic avenue for chronic diseases with otherwise limited treatment options. (904 nm; 700 Hz pulse frequency, 861.3 total joules x 11 wks) https://www.liebertpub.com/doi/10.1089/photob.2021.0057
     
    John Schumacher likes this.
  2. Coupled complex PBM and probiotic interventions can control the microbiome, improve the activity of the immune system, and save the lives of people with immune imbalances.

    PBM can influence the diversity of the intestinal microbiota, and can increase the percentage of Allobaculum, a bacterium in the category of the good ones in the intestine.

    Photobiomics
    NIR light (808 nm), PBM produced a 10,000-fold increase in the proportion of the beneficial bacterium Allobaculum in the microbiota of mice after 14 days of treatment with NIR light but not with red light.

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    The main interactions between the microbiome and the body with a healthy and unhealthy microbiome. Bacteria in the microbiota produce SCFA, influence redox signaling, influence tryptophan metabolism, activate plant polyphenols, and produce neurotransmitters, hormones, and peptides. This has the effect of promoting a thick mucus layer, an intact epithelium, and producing numerous downstream metabolomic effects. The microbiome communicates with the body through these metabolites as well as direct communication through the vagus nerve. In dysbiosis, reduced SCFA levels weaken epithelial integrity, increasing efflux of bacterial metabolites, such as proteins and LPS, contributing to an increased inflammatory response and ‘‘leaky gut.’’ Production of TMOA and p-cresyl sulfate are correlated with cardiovascular disease. 5-HT, serotonin; ACh, acetyl choline; BBB, blood brain barrier; CVD, cardiovascular disease; DA, dopamine; GPCR, G protein couple receptor; IPA, indolepropionic acid; LPS, lipopolysaccharide; ROS, reactive oxygen species; SCFAs, short chain fatty acids; T2D, type II diabetes; TMA, trimethylamine; TMOA, trimethylamine oxide.​
     

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