1. Registering for the Forum

    We require a human profile pic upon registration on this forum.

    After registration is submitted, you will receive a confirmation email, which should contain a link to confirm your intent to register for the forum. At this point, you will not yet be registered on the forum.

    Our Support staff will manually approve your account within 24 hours, and you will get a notification. This is to prevent the many spam account signups which we receive on a daily basis.

    If you have any problems completing this registration, please email support@jackkruse.com and we will assist you.

Oscillating hormones?

Discussion in 'Heal Your Hormones' started by Blue30, Jan 14, 2015.

  1. Blue30

    Blue30 New Member

    JanSz, I will schedule an appointment with my doctor and let you know what he says.

    I've also run some additional labs, as suggested above.

    Pregnenolone, MS 66 ng/dL, ref <151
    Insulin-Like Growth Factor I 194 ng/mL, ref 88 - 246
    Serotonin, Serum 124 ng/mL, ref 21 - 321
    Sex Horm Binding Glob, Serum 54.0 nmol/L, ref 16.5 - 55.9

    Any ideas why SHBG is so high? Is this related to the thyroid issue mentioned above?
     
  2. JanSz

    JanSz Gold

    Insulin-Like Growth Factor I 194 ng/mL, ref 88 - 246
    Sex Horm Binding Glob, Serum 54.0 nmol/L, ref 16.5 - 55.9

    Any ideas why SHBG is so high?
    -----------------------------------------------------------
    Good level of SHBG is 20-25

    Level of SHBG is mostly generally correlated with good health.
    Observed correlations are with

    estrogens, raising increases SHBG
    testosterone, raising decreases SHBG
    better thyroid hormone panel influence SHBG, up or down
    good Growth Hormone influences SHBG, up or down
    ------------------------------------------------------------

    both TT4 and TT3 could be higher >>>>????? Sodium-Iodide Symporter
    ------------------------------------------------------------

    When monitoring GH, or making decision about supplementing with GH
    dr Hertoghe looks mostly at

    IGF-1
    and
    IGFBP3

    caveat:
    he insist that the testing is done using RIA (manual) methodology.
    He specifically warns against the (most commonly used) methodology, chemoluminessence.
    Using RIA methodology to have sufficient GH on need to have:

    IGF-1(300-350)ug/dl, deficient when less than 250
    IGFBP3(3000)ug/dL, deficient when >4000
    ===========================================================

    For my self, I have done at LabCorp tests two different ways and got dramatically different results.

    Tests at LabCorp that dr Hertohge warns against
    Insulin-like Growth Factor 1 (IGF-1)Test Number: 010363 CPT Code: 84305
    Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) Test Number: 140152 CPT Code: 83520
    --

    Tests that dr Hertoghe would hopefully approve:
    Growth Assessment Test Group X (Growth Hormone, IGF-I, IGF-II, IGFBP-3)
    Test Code 500901 ... CPT Code 83003, 84305, 83519, 83519

    http://www.esoterix.com/prodserv/test_menu/endocrinology.asp
    http://www.esoterix.com/prodserv/test_menu/test_detail.asp?center=endocrinology&testid=1113


    ..............................................................

    ;
     

Share This Page