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One of the Best Journal Articles Ever

Discussion in 'Mitochondrial Rx' started by DrEttinger, Jan 19, 2019.

  1. Sue-UK

    Sue-UK Gold

  2. DrEttinger

    DrEttinger Choice, the only thing we control

    Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice.

    "We hypothesized that long-term continuous intake of the I. obliquus extract could suppress tumorigenesis by supporting normal metabolic reactions in the organism, including thermogenesis."

    Chaga contains one of the highest concentrations of melanin and confers upon the user all of the benefits of being fortified with supraphysiologic doses of melanin.


     
    Sue-UK likes this.
  3. Sue-UK

    Sue-UK Gold

    DrEttinger likes this.
  4. DrEttinger

    DrEttinger Choice, the only thing we control

    Let's apply some basic logic here based on what we know. CT increases mitochondrial function and density and is a thermogenic process. Chaga increases thermogenesis within cancer cells and contains melanin which we can assimilate into our system improving human photosynthesis. Astaxanthin and spirulina contain photoreceptive pigments that we can absorb and incorporate into our system increasing our ability to absorb light - human photosynthesis. Exposure of our skin to the Sun increases melanin production increasing the dissociation of water which produces energy (electrons) as a byproduct - human photosynthesis. As we can see here we have control of this process and can biohack it if we want. Most though spend 97% of their day indoors under some form of blue light.

    To the degree, cancer is a disease of the absence of sunlight light, being cancer-free is to how much natural sunlight you can receive and how well it's absorbed and converted into energy.
     
  5. JanSz

    JanSz Gold

    cancer is a disease of the absence of sunlight light

    .
     
  6. JanSz

    JanSz Gold

    upload_2019-10-30_10-0-3.png
     
    Last edited: Oct 30, 2019
    DrEttinger likes this.
  7. JanSz

    JanSz Gold

    I could use help here.
    We are synthesizing 3000 liters of matrix water daily when at rest.
    That produces so much energy that we would burn instantly if not that other reactions are happening simultaneously, that use up that energy.


    Dissociation is the process by which a molecule separates
    -----
    Bonds are broken. When bonds are broken, energy is absorbed.
    Therefore, when water "dissociates" into hydrogen and oxygen, the molecules absorb energy.
    Of course, not all reactions that break bonds are endothermic (think ATP being split into ADP and inorganic phosphate, an exothermic reaction).
    ----------

    Why is the dissociation of water an endothermic reaction?
    https://www.quora.com/Why-is-the-dissociation-of-water-an-endothermic-reaction

    ...........
     
    drezy and DrEttinger like this.
  8. DrEttinger

    DrEttinger Choice, the only thing we control

    Jan,

    That data is above my paygrade. I've never given that enough time to do justice to it. I will though, at some point, really put some time into it.
     
  9. Sue-UK

    Sue-UK Gold

    I thought this was interesting https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653983/ Evidence for the ectopic synthesis of melanin in human adipose tissue including
    "In conclusion, our study demonstrates for the first time that the biosynthesis of melanin takes place in visceral adipose tissue of morbidly obese subjects"

    In the Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice study already linked
    section 3.1 results
    "First, we examined the effect of continuous intake of the I. obliquus aqueous extract on body weight of mature adult mice (12–15 weeks) and middle-aged mice (30 weeks). The results indicated that middle-aged mice lost about 8% of weight after 17 days of drinking I. obliquus extracts compared to the control group (Fig. 1A); there was no difference in water intake between the two groups (Fig. 1B). Interestingly, the I. obliquus extract caused no changes in body weight or the amount of consumed water in mature adult mice (Fig. 1C and D). These data suggest that the intake of the I. obliquus extract promoted lipolysis in developed fatty tissue; therefore, in further experiments we used mature adult mice (12–15 weeks) to avoid the influence of body weight difference between control and treated mice observed prior to tumor implantation on subsequent tumor growth."

    So its whether there's a connection with melanin in chaga downregulating ectopic melanin biosynthesis? :confused:
     
    drezy likes this.
  10. DrEttinger

    DrEttinger Choice, the only thing we control

    I feel that anything that could reduce mitochondrial ROS produced from the oxidative stress of obesity would downregulate ectopic synthesis of melanin in (obese) adipocytes.


    https://pdfs.semanticscholar.org/eb7c/e38ef6bb3144059b518bc83411b6fd0f975f.pdf

    It has been demonstrated that the expansion of adipose tissue in obesity is mainly characterized by hypertrophy, accompanied by oxidative stress and inflammatory environment influenced by disturbances in energy and lipids storage [37,38]. ROS produced from mitochondrial oxidative stress play an important role in regulating adipocyte diوٴerentiation of mesenchymal stem cells (MSCs) [39]. We believe that ROS induced adipocyte diوٴerentiation is an adaptative response to hypertrophy stress. To relief hypertrophy and associated oxidative stress, adipose tissue attempt to reinstate metabolic homeostasis (My addition - via ectopic synthesis of melanin.
     
    Sue-UK likes this.
  11. Sue-UK

    Sue-UK Gold

    Last edited: Nov 2, 2019
  12. Sue-UK

    Sue-UK Gold

    drezy likes this.
  13. Michalis

    Michalis New Member

    So consider the broadband absorption of light from melanin. In an ideal world it absorbs the sun's spectrum it splits water and provides us with energy. What happens if it starts absorbing on other wavelengths, like nnEMF? Does is still produces current? What exactly is happening? Because this is the implication i can see here.
     
  14. Sue-UK

    Sue-UK Gold

    https://pharmacy-nutrition.usask.ca...r-uses-fungi-to-protect-against-radiation.php
     
    Duchess Sunshine and Michalis like this.
  15. Michalis

    Michalis New Member

    Really interesting!

    Some species of mushroom have developed the unique ability to not only survive in a radioactive environment, but actually thrive in such severe conditions. These growths, known as radiotrophic fungi, are believed to use melanin as a tool to convert gamma radiation into energy for growth. And Dadachova believes this fungal life could be used as cost-effective, sensitive biological detectors of nuclear fallout.

    So while you digest the fungi the person will absorb the melanin and the melanin will "catch" the aberrant energies of the environment. All good so far . Those energies will be re-emitted though. Does melanin convert them to a friendlier form of energy , lets say uvc that can be used with deuterium as long as it is in the gut or circulation?

    i found this and it seems interesting!
    https://www.nature.com/articles/npre.2007.1312.1.pdf?origin=ppub
     
  16. JanSz

    JanSz Gold

    upload_2019-11-12_15-16-56.png
     
  17. Michalis

    Michalis New Member

    No i don't think that is the case, it is a just a part of the story..
     
  18. Sue-UK

    Sue-UK Gold

    "Melanin is to the animal kingdom like chlorophyll to the vegetal system. "
    "If true, goodbye mitochondria, hello melanin"

    I don't think that's accurate because melanin is also important to the plant kingdom. For example melanin in bark, and seeds. Alone, it speaks of dormancy. When the right conditions for photosynthesis happen, a seed grows, leaves appear ….. Maintaining or growing biomass. I think there's more of a haemoglobin to chlorophyll link and a melanin to (melanin containing) plant lignins link. Apart from any water splitting, if mitochondria are heat dissipators, the biomass we eat provides heat that can be used by melanin to further split and reform water. As well as maintaining our own biomass, I would suspect that for humans this thermoregulation promotes sleep every night as opposed to animals forced to bouts of torpor or hibernation dotted with bouts of euthermia, in an effort to survive food scarcity or extreme cold.

    Just musings, still working through the book, but at the moment its more a case of hi mitochondria, meet melanin … :D
     
    Michalis likes this.
  19. JanSz

    JanSz Gold

    "Melanin is to the animal kingdom like chlorophyll to the vegetal system. "
    "If true, goodbye mitochondria, hello melanin"
    ----
    Possibly this will clarify what I am interested in.
    ----
    Everybody and his brother say how important ATP is and that we make so much of it within a day (24 hrs) that it is really close to the body's weight.
    Impressive description, and tell's me not much.
    Reading that, I still think that the human body runs on about 2000calories/day (from food).
    But
    when I see that to make (this important ATP) water is synthesized, I am not particularly impressed, until I see how much water it is, and especially that with that energy, you can lit couple of football stadiums for 24hrs. So it is thousand's times more than the puny 2000calories from food.

    When I think that I nailed something important, dr Boros tells me that I am ok with what I posted to him, but, but actually, we go thru much much more energy daily.

    So at this point, I would like to assign numbers of KiloWattHours to melanin's activity.
    If it is less than 2000calories a day, I do not care.
    But it looks like energy synthesized during matrix water production (however big) is minute when comparing to activities that melanin control.
    Where is that energy coming from? How many KiloWatHours we use daily?
    How is it replenished with (so little energy that is coming from Sun in real-time)?
    Eventually, that energy will get exhausted. How long will it support life on Earth?
    -------
    What is obvious to me at this time is that the (real-time) solar energy involved in our life, on the equator or far over from tropical zones, is a minor player.
    Real-time solar energy is an information source but not an energy source.

    ---------------------------
     
    Last edited: Nov 13, 2019
  20. Sue-UK

    Sue-UK Gold



    Perhaps there's some theoretical way of calculating it, but I'm not sure that in natural conditions it would be easy to assign a number of kilowatt hours to melanin because the environmental conditions are constantly changing, and melanin involves more than just visible, UV and IR light. Melanin's activity and water splitting capability increase in strong sunlight, and diminish in darkness. IIRC Dr Herrera said in an interview that melatonin is a natural inhibitor of human photosynthesis.

    If biomass is considered as a form of stored sunlight, how much biomass (calories) we need to eat (or eat to convert to fat) to maintain our own biomass, cover overnight or seasonal temperature variations and food scarcity etc depends on a lot of variables. But real time solar energy (or lack of it) seems to be related to energy as much as information.

    Only had a quick skim of this but will get round to printing it out ….

    https://patents.google.com/patent/WO2007102724A2/en
     

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