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MRI With Contrast

Discussion in 'Optimal Labs' started by persistence, Feb 6, 2015.

  1. persistence

    persistence New Member

    Maybe only Jack would have an opinion on this issue, but does anyone have data on how much less effective an MRI would be at finding:

    * pituitary tumor
    * aneurysm

    if done without contrast?

    Would the use of a high resolution 3 Tesla MRI machine change that answer?

    My doctor wants me to get an MRI with contrast, and I am concerned about the gadolinium contrasts that are used in these tests. There are lawsuits against the companies that make those contrasts, and there are peer reviewed studies showing non trivial percentages of people who get those contrast studies later develop kidney problems. The chelate forms of the contrast supposedly are safe, but there is some evidence that the toxic gadolinium gets absorbed directly anyway.

    The bottom line: is the MRI without contrast only 30% as useful? 90% as useful? I'm trying to understand the tradeoffs here.
     
    billy likes this.
  2. billy

    billy New Member

    I need to know the answer to this as well.
    :bump:
     
  3. Jack Kruse

    Jack Kruse Administrator

    MRI without contrast is not ideal for the tumor. It is useless for an aneurysm.........MRA is better option for CV lesion
     
  4. billy

    billy New Member

    Thanks! ....and dammit - the sides look nasty.

    Then there's this 2015 Radiology published study;

    "Transmission electron microscopy showed that most of the gadolinium deposits were in the endothelial walls. However, 18% to 42% of the gadolinium appeared to have crossed the blood-brain barrier and was deposited in the neural interstitium.

    'Certainly, that wasn't expected; we didn't think these agents could do that,' said Dr McDonald."
    ….

    "These authors have tried to exclude known causes of blood-brain barrier breakdown, leading to the clear suggestion that this retention of gadolinium in the endothelium and brain parenchyma is not due to local effects of tumor or inflammation."
    - Dr Nuwer

    http://www.medscape.com/viewarticle/842107#vp_2
     
  5. Jack Kruse

    Jack Kruse Administrator

    When BBB breaks down K+ inside cells have issues.........and neurons swell and diffusion weight imaging is bad........= MS = PD = FM.


    HOW ARE PD AND FIBROMYALGIA THE SAME BUT DIFFERENT? Both come from a lack of light at a particular surface. = PD = lack of dopamine in the RPE........this is why Parkinson people loss muscle mass and it even causes their special non expressionless faces...........PD is usually related to a lack of full spectrum sunlight getting to the eye to build dopamine and melatonin locally in the retina.
    If the eye doesn't get the stimulus of UV/IR light neither does the frontal lobes nor the brainstem = substantial nigra = PD.
    What happens if you live your life 99% indoors and always around fake light always covered up with clothes or fake light? Fibromyalgia = skin surface defect = this implies PD and FM are somehow linked in quantum fashion doesn't it? HOW? Where does skin and brain come from in a zygote? NEUROECTODERM.................BOOM
    DETAILS: When water in your cell can not carry the right amount of energy life can not grow. Think if a plant. If it has little water and lots of sun will it grow and live well? No. Realize water and the level of potassium (K+) in a cell are linked. Energy is tied to K+ ion concentrations and this is connected to ATP levels at cytochrome 5, the ATPase. K+ also links to water molecules and in turn to ATP molecules stochastically. For every 0.3 mEq below 3.8 mEq that potassium is on a standard blood lab draw, means there is 100 mEq deficit of potassium INSIDE a cell. This deficit cause a mitochondria to consume more calcium and it swells. This slows ECT because it increases the distance of the respiratory proteins. The atomic size change altered the local geometry below your skin where your muscles are. This is where muscle pain and FM come from. This is linked to the redox potential in a cell (amount of UV light confined) because it is linked to the electrostatic attraction in a cell. This is huge for potassium, because its K+ ion has the unique ability in “gluing of water”. Gluing = EZ of Pollack or the AI hypothesis of Ling.

    Potassium ions are able to glue water because the ion's atomic radius allows it to polarize in sunlight. Sunlight is unpolarized..............K+ ions is the initial polarizer of sunlight inside cells. When somebody is in an environment that causes the dielectric constant of water to lower from 78 for any reason (LOTS IN MODERN WORLD), the polarization of the ion becomes smaller than cell water. This cause a huge electric problem in the cell because polarization energy of K+ is subtracted from Coulomb energy. Normally K+ is more polarizable than water, so polarization is added to the Coulomb energy in a cell. When fluoride or bromide, from toothpaste or grains for example, are added to a cell dielectric collapse occurs. This is precisely how the dielectric constant in water is destroyed.

    In the normal state of affairs in wellness in the sun, this allows potassium to function as the optimal "photo-electrical adapter" to transfer energy throughout the cell coherently. It is also massively important in patients with dielectric collapse because intracellular dehydration from non native EMF completely ruins this relationship and this is why they find it so hard to get better fast. ATP is designed to unfold proteins fully to open their carbonyl and imino side chain groups on all amino acids to intracellular water. This action allows binding and polarization to separate water into subatomic particles that are positively and negatively charged. This action is called building or expanding the exclusion zone (EZ) of water. Dr. Gerald Pollack's experiments showed these effects. Dr. Gilbert Ling proved by experiment that each molecule of ATP in a cell controls 8,800 water molecule binding sites and 20 potassium ions to allow water to become structured inside every cell of your body.

    The first step in photosynthesis and in mitochondrial oxidation/phosphorylation of electrons is to charge separate water...........now you know the why K+ and sunlight help muscle pain and fatigue reverse. UV and IR light build dopamine and melatonin which stimulate muscle growth and entrain properly function by maintaining the respiratory proteins in muscle mitochondria. Light is the most powerful drug we have.............especially for muscles. Get some sun.............
     
    billy likes this.
  6. billy

    billy New Member

    Thanks so much Dr K.
    I obsessively put skin in sun and look into blue sky.

    You send me down the rabbit hole again and I'm grateful for that.
    'Life at the Cell & Below' is great but taxing as hell.
     
  7. HopingMom

    HopingMom New Member

    My son was still peeing out gadolinium at 9 months after MRI w/contrast. Poor methylation-yes, but geese nothing like adding to the load.
     
    billy likes this.
  8. billy

    billy New Member

    Wow HopingMom - did you test the urine for it, or was it obvious to the senses?
    Have you researched high fat/low carb eating?
    Have you researched Dr Seneff?
    https://people.csail.mit.edu/seneff/

    I had a blood draw from the same arm 3 days later and it HURT!

    I've had many draws and donate a lot - with zero issues. I think the phlebotomist just gored a nerve. I still have distal radius area pain.

    My Dr wanted me to get neck x-rays, which were fine. I'm now giving cervical traction a try then going to pester Dr K if that isn't it.

    I think it's my root canal, however. That's when weird stuff started up.
     
    Last edited: Apr 21, 2016
  9. HopingMom

    HopingMom New Member

    Yes, it was on a urine test. Yes, we have been on every diet known to man.
    I do really enjoy Stephanie S-she gives me good vibes.

    I guess my opinion on medical testing, conventional, etc would be that it would be dependent on the individual. Obviously for my son we needed to do the MRI and I wouldn't change that but would have more proactive in researching and probably would have done some prepping to help get the contrast out...I guess that is learning though...however, I guess I feel if it was me I wouldn't want to go through tests, etc I think I would be much more sick feeling knowing that a test proved that I had something that sounded scary like a tumor or cancer or something that has been pre-programmed into us to make us scared.
     
  10. Sandra

    Sandra New Member

    I opted to have an MRI instead of a mammogram to avoid the radiation. When I arrived for the appointment today I was told there would be a contrast dye used. It surprised me a little as I'd not been aware it would be required and didn't have any time to look into it. I agreed as the radiographer said it was fine (of course!). Now I am annoyed at myself as I have found out that the gadolinium is a heavy metal and I just want to get it out of my system. I don't have any renal issues and have always had fine kidney function. Since the appointment I've been drinking loads of reverse osmosis water (probably silly to think that will flush it out if it's already absorbed somewhere!). I on a magnetico mattress. I usually have lots of sun in my life too. Is there anything more I can be doing to remove this quickly? Thanks :)
     
    Mito1 likes this.
  11. Jack Kruse

    Jack Kruse Administrator

    Dialysis.........but i would not do that. You should be fine. Just limit your MRI imaging in short periods of time.
     
  12. Mito1

    Mito1 New Member

    the contrast is pretty dangerous stuff. The actor, Chuck Norris, wife almost died from a one time exposure to contrast dye. The contrast has been banned in Europe - it's not allowed at all.


    Chuck Norris sues for $10M over MRI chemical he says poisoned wife

    https://www.usatoday.com/story/life...mri-chemical-he-says-poisoned-wife/824839001/







    .
     
    Jenifer Caplan likes this.
  13. Sandra

    Sandra New Member

    Thanks Jack. I am feeling fine and have no symptoms so hopefully all is OK and now I know better for the future.
     

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