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More on Factor X:

Discussion in 'Factor X' started by Jack Kruse, Jan 4, 2013.

  1. Jack Kruse

    Jack Kruse Administrator

    Mammals make body heat.......Why did this help them after a bollide hit the Yucatan 65-67 million years ago?

    The Evolution of Body Heat?

    When oxidized, the great majority of our food and stored energy goes to the production of HEAT. What governs this? It is multifactorial but adrenaline, thyroid, cortisol and mitochondria quality are just a few [2]. Active tissues contain more mitochondria. Heat makes us mammals and birds. We have hot bodies, precisely 37C for the great majority.

    In the 'Hot Brain: Survival, Temperature, and the Human Body' the authors theorized that temperature gave us advantages over eukaryotic infections (yeast, fungal origins -- we are eukaryotic) which plagued bird/reptile species which were not armed with high 37C temperatures or fever-inducing capabilities [3]. It is a very interesting theory. Control of thermoregulation (heat loss v. heat gain) is believed to have evolved in the brain of therapsids. Our sinuses are larger. Mammalian brains have a Circle of Willis where 4 arteries (internal carotids and vertebral arteries) provide a complete internal brain circulation with collaterals, such that despite blockage of one or more of the 4 major arteries circulation in the brain and to the body remains intact. Unfortunately only 25-33% of us have a 'perfect' classic circle of Willis; others have degrees of narrowing or asymetry in certain areas or another. Photos courtesy: Hot Brain, pp. 44, 142.

    Recently a microbiologist, Casadevall, from Albert Einstein had the same theory that the rise of mammals can be attributed to 'endothermy and homeothermy [which] are thought to contribute to mammalian resistance to mycosis by creating a thermal exclusionary zone that inhibits most fungal species. The remarkable resistance of mammals to mycotic diseases is probably a combination of a vertebrate immune system, with both innate and adaptive arms, and elevated body temperatures... The currently favored hypothesis for the demise of dinosaurs and end of the age of reptiles is a bolide impact approximately 65 million year ago with the possibility that other events, such as increased volcanism, contributed to disrupting the cretaceous ecosystem. That ecological calamity was accompanied by massive deforestation, an event followed by a fungal bloom, as the earth became a massive compost. Although one cannot know which spores were present at the time, the likelihood that pathogenic fungi existed at the K-T boundary is enhanced by the finding that the potential for pathogenicity probably arose independently several times in evolution...'[3]

    'Although we do not know the timeline for the recovery of the planet climate, it is estimated that photosynthesis was shut down for 6 months and climate cooling persisted for at least 9 years, and the occurrence of a fungal bloom sufficient to have left fossil evidence implies that surviving animals were exposed to massive numbers of fungal spores. The darkened skies and cooler temperatures that accompanied the K-T cataclysm would have shielded the sun and reduced the ability of ectothermic creatures such as reptiles to induce fevers by insolation, a necessary activity for protection against fungal diseases. Hence, it is reasonable to posit that ectothermic creatures unable to induce behavioral fevers and in weakened states from environmental stress would have been at a severe disadvantage relative to small mammals with their innate thermal exclusionary zones for fungal growth. Further complicating the situation for reptiles is that eggs can be vulnerable to fungal attack, whereas mammalian progeny would be protected in placentae.'[3]- From Dr. B. G.
  2. Shijin13

    Shijin13 Guest

    pretty cool... so we're endothermic - due to the ability of our mitochondria's ability to produce heat from the uncoupling of bonds when ATP is transformed to ADP and energy is released. This energy management system allows eutherian mammals to fight off the fungal explosion in the environment through fevers, thus eliminating our susceptibility to those organisms. Three questions for you: so, how does the Cold Environment of the post KT event world leverage Heat Shock Proteins? is this part of the process or is it a side process as a result of the Cold Environment? How does the epigenetics and circadian mismatches that Factor X leverages make us more vulnerable to similar organisms - such as MRSA or candida overgrowth? It's not just the carbs that's contributing to this vulnerability - our environment is also at play with regard to our susceptibility, correct? Thus our mitochondrial in-efficiency, as a result of electron loss/leakiness through consumption of carbs is limiting our ability to fight infection through endothermic regulation.
  3. Jack Kruse

    Jack Kruse Administrator

    all food puts at risk........cold is primordial. CT 2 all over again. 65 million years ago was a reversion back to primordial. Life has faced this before........the proof is found in our ability to adapt back to the mean........heat shock proteins came much later in evolutionary time to allow us to live away from the mean.......got it?
  4. Shijin13

    Shijin13 Guest

    got it....

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