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MITOCHONDRIAL THERMODYNAMICS DIY LESSON THREAD

Discussion in 'Mitochondrial Rx' started by Jack Kruse, Jan 16, 2023.

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  1. Jack Kruse

    Jack Kruse Administrator

    There is this funny peculiar thing about Earth though. It has a magnetic field that protects it surface from most of the electromagnetic radiation and force from the sun. This implies too much electromagnetic force is not good for life. This insight has not been made by many. Earth also has a magnetic core made up of iron and a surface that has water. These unusual sets of circumstances are the ground rules that Mother Nature must deal with to make order from the chaos here on Earth. When you really think deeply about what all these factors do in unison, you begin to see the recipe for life differently. You begin to see why life organizes around a cell that is loaded with liquid crystalline semiconductors at its core. They are made of water. Matter, like proteins, is made of a carbon backbone.
    Carbon does not have a high affinity for water naturally. So this physical property of carbon and water interaction could be used to Mother Nature’s advantage when you consider what impacts this has on energy distribution on Earth. When water is confined to tight spaces, as you would see in a cell, it restricts the distribution of energies inherent in the water molecules' molecular structure. This means hydrated carbon is a great place to store energy for a long time so you can tap it when you need it.

    This is important because by allowing for this naturally, the water molecules end up with a lower average energy than if they were in regular bulk water from your swimming pool. This implies, just restricting water to a “tight room”, it becomes energetically favorable for the water to enter small collagen fibrils. It turns out that the collagen molecules in us can and should be described as a dissipative structure.

    They become self-organized into a triple helix when these strings of amino acids are surrounded by water. This water around collagen strands, however, then does something unusual. Water molecules separate from one another and charges separate and electrons & protons are freed to roam. Water becomes a layer of hydroxyl ions and protons. The freed electrons adjacent to water electrify the collagen backbone and the result is a self-assembled triple helix.

    Nothing else is required. Collagen is the most common protein in the body = collagen is the most common dissipative structure in humans. The gelatin in your bone broth is collagen in water with no charge separation happening. If you pass an electric current through your bone broth guess what happens when you look at it under a microscope? You see triple helices form. When water binds to collagen that is energized by the sun's photons this is when water chemistry does some amazing things. Right next to collagen forms an empty space called a coherent domain that has a large net negative charge and it excludes protons with a positive charge creating a battery that controls all proteins in cells. This includes enzymes that run all metabolic pathways. Next to these coherent domains are delocalized electrons that are separated from water molecules. Next to the electron layer, we see a dense layer of protons that come from the freed hydrogen in water. It appears collagen allows water to separate into its constitutive parts & charges to form groups of charged particles.

    It is almost like water acts like an “electric wire” to activate collagen to life.
     
  2. Jack Kruse

    Jack Kruse Administrator

    So why is just confining water to a tube a big deal inside a cell? Because water has special quantum abilities in this state that it does not have in your bathtub.

    Think of this analogy to hammer home this point home; in a crowded subway, people’s movements are restricted compared to what they are on the streets above, and hence the range of their energy distribution is narrowed towards the lower end of the energy scale. Restricting movement gives you control over the protons and the electrons.

    Both of these are charged particles. The electromagnetic force only deals with charged particles. Restricting the movement of charged particles allows you to store energy everywhere in a cell. It also gives you supreme power of electrons and protons in cells use light as an optical tweezer.

    You might begin to understand then why biology uses the Schumann resonance at 7.83 Hz, and its harmonics, to control how biochemistry works. When you understand this simple example of how molecular crowding acts on charge separation and development, you begin to see why restricting water movement in a cell matches perfectly with the way life would be organized on this planet. This is because the Earth naturally has the Schumann resonance coming from its core with a ton of water on its surface. The Schumann resonance is only 7.83 Hz and resides on the lower scale of electromagnetic forces that exist on the surface of our planet. The two physical things are found naturally on Earth and become coupled together as a dissipative system and this is coupled to collagen in your cells.

    As light energy from the sun is pumped into the cell, proteins begin to act in unison to begin building the framework of the semiconductor of a quantum cell. The most common element on the entire planet is iron, a transition metal. This metal is vital in many critical pathways in metabolism and is also controlled by electromagnetic force. I believe it is done by molecular resonance. I think by using various oxidation states of ions in cells locked to their highly mobile D shell electrons, these things can be used as off and on switches.

    This also paints a clear picture of why ionizing radiation is so damaging to a quantum cell. Ionizing radiation is on the higher scale of the electromagnetic scale of forces. The higher force diminishes the production of water in cells and water already made in cells to lower charge separation inside of cells. With free electrons and protons redox power drops.

    If our cells had massive sizes with free-floating water with lower amounts of transition metals in them we could handle much higher electromagnetic energies to survive, but we don’t on Earth, therefore we can’t live in these environments. To make it in this environment, life likely would have to use a different liquid, other than water, to form hydration shells around its carbon backbone proteins to better handle the higher electromagnetic forces that would be present. But because the conditions on our planet favor the lower end of the energy electromagnetic spectrum naturally, all chemistry, and therefore, all biology has to be dictated by this scale of energies in order to create order from the chaos on Earth in a dissipative system. That is what a cell is doing.
     
  3. Jack Kruse

    Jack Kruse Administrator

    The point of the last 4 posts here is this: decentralized physicians have to take the things Gilbert Ling said in 1952 and begin plugging them in to things QFT and AMO physics has already proved over the last 65 years while biology made up words to put in the crossword puzzle of life.

    Most people buy beliefs and not the real benefits. This is why Occam’s razor “beliefs” persist in biology. Occam’s razor is what most believe to be true but it is not always the parsimonious way nature works……….when you think something sounds “kooky”…….it might be that “kooky” is parsimonious after all. Someone on my forum recently remarked that she changed her beliefs because she was not getting the results she wanted listening to her doctor’s advice. She read my blog and decided to give crazy and shot, and low and behold it worked! And the reality is most of us just never saw “this reality” in your own fishbowl of understanding life. This is why it took so long for the photoelectric effect, theory of relativity, and the 30 step process of photosynthesis to be fully accepted by science. They all break Occam’s razor rule of parsimony, yet, all have been experimentally found to be true in our universe. Ling’s idea, was radical and not parsimonious, but it too, fits the way a quantum cell works. He was way ahead of his time, so far ahead that no one could fathom what his science implied. That no longer is the case. Experiments in quantum and AMO physics and biology have finally caught up to Ling’s work now. It is time we make sense of it for your health.

    Gilbert Ling's work in biology was among the most difficult things I conquered in my life. I did not quit because it was difficult to understand. I became much more interested in building upon what he uncovered.

    My work in quantum biology is a very difficult read for many. This science has patterns & references to physics and physical chemistry, which usually repel humanists. But do not be afraid. Even if you do not understand everything, my work will sharpen your appetite for knowledge
    Quote Tweet


    Membrane theory remains a sacred cow. It is a tyranny of belief that underpins the centralized healthcare system.

    [​IMG]
    with any of it.
    [​IMG]

    To all those pushing centralized medical beliefs/tyrannies, you have forgotten the tenet “I will remember that there is an art to medicine as well as science, and that warmth, sympathy, and understanding may outweigh the surgeon’s knife or the chemist’s drug.”

    [​IMG]
     
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  4. Jack Kruse

    Jack Kruse Administrator

    What is a disease to a decentralized MD? A process that is associated with energy loss and entropy gain.

    Health is a process where solar energy is pumped into cells and stored and entropy decreases. This is the blueprint of how a dissipative structure operates.

    Sometimes the greatest thing to come out of all your hard work isn't what you get for it, but what you become for it. Authenticity always and absolutely carries a demand and duty for us. You must speak out, to the best of your ability, shake the spiritual tree, and shine your inner flame into the eyes of the complacent. You must let that realization rumble through your arteries and rumble through those around you. Make a pact with yourself today to not be defined by your past. Today, don't just be a consumer, be a creator of life. Somewhere inside you is a masterpiece waiting to be exposed. https://www.linkedin.com/pulse/why-did-neo-choose-red-pill-jack-kruse/

    Sharing your ideas with the world can be scary or exhilarating. Your perspective paints that expectation. Do you have a dream that seems so large, it just seems like it can't come to fruition? I do. I share those ideas in my posts. It is time to share another. I believe all dreams come true if we have the courage to pursue them. It is always easier to make a dollar off a dream, but it is a lot tougher to make a difference with one. I think every post is going to do for one of you.
     
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  5. Jack Kruse

    Jack Kruse Administrator

    The environment is everything you see, but more importantly, everything you don't see but your cells sense. When your cells sense these waves you can bet a colony of mitochondria is deciphering this code as well.

    Tweets 24-44 should be eye-opening to centralized medicine/science to show them how much they are missing.
    https://threadreaderapp.com/thread/1513673713673285636.html
     
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  6. Jack Kruse

    Jack Kruse Administrator

    MITOCHONDRIA IS WHERE MELATONIN IS CREATED. If you have mitochondrial heteroplasmy, you cannot make the appropriate amount of melatonin in the mitochondrial matrix, and disease results. The reason why disease and poor sleep are linked is not what most people think. Few of them realize melatonin is a proxy for mitochondrial damage. Recent C19 papers have uncovered this link that was made in the literature 8 years ago. My tribe knows about it. Do you?

    Mitochondria are the major site of free radicals and related toxic species generation. Melatonin has been consistently shown to not lessen the formation of ROS/RNS at the mitochondrial level, thereby protecting against oxidative or nitrosative damage to electron transport chain proteins; it also limits lipid peroxidation in the inner membrane, thus favoring electron flux and ATP production.


    https://onlinelibrary.wiley.com/doi/10.1111/jpi.12026
     
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  7. Jack Kruse

    Jack Kruse Administrator

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  8. Jack Kruse

    Jack Kruse Administrator

    The Nobel Prize for physics in 2016 was given for the discovery of topologic insulators (TI’s).

    Topological insulators conduct electricity on their surfaces but do not conduct the current deep inside their cores. This limitation allows the cell to control Brownian motion in the cell to maintain the low entropy state I mention above.

    This helps explain why DNA’s surface is highly coiled and coated with histones, chromatin, and methyl groups when it is kept in its “quiet state” (non-dividing)

    It also explains how it can receive photo-electric instructions on its surface and transfer that information through the hydrogen bonding network (proton tunneling causing flickering) that surrounds nucleic acids to run the epigenetic programming it contains deep within. What happens on its surface can awaken the code of life buried deep below its double helix. This process is all possible because DNA AMO structure is capable of inducing a change in base pairs by altering the hydrogen bonds on its surface because of how Dirac fermions operate.

    In physics, a Dirac fermion is a spin-½ particle. Take a look here to see a video on it.
    https://www.instagram.com/p/CnPiUugho2Z/

    In condensed matter physics, low-energy excitations in graphene and topological insulators, among others, are fermionic quasiparticles described by a pseudo-relativistic Dirac equation. I think DNA acts like a fermionic quasiparticle. Fermions include all quarks and leptons and all composite particles made of an odd number of these. Some fermions are elementary particles (such as electrons), and some are composite particles(such as protons). I think this is why mitochondria only deal with electrons and protons. I also believe this is why neutrinos might be a player in biology. I think fermions and light interactions are how starlight is transmitted to living cells.

    The Standard Model recognizes two types of elementary fermions: quarks and leptons. In all, the model distinguishes 24 different fermions. There are six quarks (up, down, strange, charm, bottom, and top), and six leptons (electron, electron neutrino, muon, muon neutrino, tauon and tauon neutrino), along with the corresponding antiparticle of each of these.

    Claude Shannon taught the world that information flows via entropy. All clocks should be thought of as flowmeters for entry. This includes the biological circadian clocks in cells. Wheeler taught physics that information and energy are one and the same thing. Shannon’s mathematics from his 1948 paper advanced the linkage of entropy and information. Shannon's paper also told us anything can be a message.
    I believe sunlight messages for mitochondrial DNA and nuclear are controlled by "fermion messaging". DNA is informed about what to do with optical information from the sun via mtDNA signaling (optical and free radical) and this message is transmitted over water's hydrogen bonds adjacent to proteins in a cell. DNA is a very complex topologic insulator that is an antenna for our star's information.

    Water makes up 99% of molecules in every cell. Water is a very small molecule that has more hydrogen bonds in it than any other compound. Liquid water contains the densest hydrogen bonding of any solvent, with almost as many hydrogen bonds as there are covalent bonds and hydrogen bonds in its structure found anywhere on Earth. These two bonding networks are the binary code in water. Just as a computer can use a 1 and 0 to create digital information on the internet, hydrogen bonds create the internet in your cells. Shannon taught us
    the information content of any kind of message could be measured in binary digits or just bits.

    Water's hydrogen bond network changes at a pico and femtosecond level in any environment. Inside a cell, its atomic arrangement is controlled by electrostatic forces in a cell created by the redox power of the mitochondria in that cell. These hydrogen bonds can rapidly rearrange in response to, light frequencies, charge density, and changing conditions and environments (for example, solutes like K+ in a cell).

    Shannon demonstrated, contrary to what was commonly believed in the 1940s, that engineers could beat their worst enemy ever: transmission errors-or in their technical jargon, "noise." Noise is anything that disturbs communication. It can be an electric signal in a telephone wire that causes crosstalk in an adjacent wire, a thunderstorm static that perturbs TV signals distorting the image on the screen, or a failure in network noise to increase the energy of the transmission signals or send the same message repeatedly-much as when, in a crowded pub, you have to shout for a beer several times. Shannon showed a better way to avoid errors without wasting so much energy and time: coding. Nature does the same thing.

    She takes the message in the hydrogen bonding network of water that surrounds every protein and encodes that information in fermionic code in mRNA, mtDNA, RNA, tRNA, and DNA.


    Coding is at the heart of information theory. All communication processes need some sort of coding to limit the noise and create a high-fidelity signal that doesn't degrade. Water preserves the information and transfers it to nucleic acids via hydrogen bonds. Just as the telephone system transforms the spoken voice into electrical signals. In Morse code, letters are transmitted with combinations of dots and dashes. The DNA molecule specifies a protein's structure with four types of genetic bases. Digital communication systems use bits to represent or encoded information. Each letter of the alphabet, for example, can be represented with a group of bits, a sequence of zeroes, and ones. You can assign any number of bits to each letter and arrange the bits in any way you want. In other words, you can create as many codes as desired. Cells have done this to run life's program.

    The interactions of electrons in a solid or liquid crystal change space in abstract ways. If you look at the picture below you can see odd shape and size changes and this leads to the different thermodynamics of what is possible on the surface. Many TI’s develop “holes” where electrons are absent and this allows them to act as P-type semiconductors then there are adjacent regions that are extremely electron rich that can act as an N-type semiconductor. Those positive and negative regions can act like “charges” and can lead to striking effects. For example, an insulating material (phosphorus) can become conductive at its surface when sunlight hits it. Phosphorus has ten atoms that stick directly out from the surface of DNA when you look at it from an axial view. See figure C below. Those ten atoms are surrounded by 447 water molecules to form part of the TI in DNA. The addition of phosphorus and iodine in the liquid crystalline water networks creates a “playground of charges and spins” in fermions to control how DNA should react to the electromagnetic signal from our star on its surface.

    [​IMG]

    Note the ten phosphorus groups sticking out to bind with coherent domains in water as DNA unwinds above

    Within the heavily condensed and coiled state DNA structure tightly holds atoms (lowering entropy), electrons, and photons in one “spin state”. When DNA is uncoiled by electromagnetic signals from our mitochondria on its surface, light is liberated from the double helix and the surface template of hydrogen bonds radically changes its “topology” by altering the spin states of fermions in the DNA crystal. This can turn on and off DNA replications
    The spins of electrons/protons (H+) are not only manipulated by magnetic fields (mitochondria) but also by electrical fields (proteins side chains) and can be used to collect and store information from electrons or the photons they carry. All magnetic drives use spintronics today to magnetically store data on hard drives. It appears DNA uses many of the same ideas but it does it on hydrated carbon-based semiconductors in cells.


    We already know a leaf can do it via photosynthesis and so can a European Robin using a light inclination magnetic compass in its eye. In my humble opinion, this process works in all animal tissues to create the many species of animals we all observe in the classical world we inhabit.

    Topology is a branch of mathematics focused on the fundamental shapes of things as they change. In cells, proteins can vary their size and shape based on the light energy that is added or subtracted from their bonds. In this way, life can be considered a quantum computer that is working in parallel with a quantum universe that also runs on light. The fermionic messages are information buried in terrestrial solar light wave frequencies in the sun that can be magnetically stored in a thin film of water surrounding nucleic acids, using non-linear aspects of light. DNA is the ultimate topologic insulator or superconductor suspended in a superfluid of coherent and noncoherent water that imprints information and conducts electrons, protons, and photons in different ways. This Nobel Prize may soon get biology away from its “solution-based ideas” in biochemistry books and push them toward quantum biology which uses a solid-state foundation. That is what this Nobel Prize means to me in 2016. The state of fluctuation of the hydrogen bonding network that light brings creates probabilities in a cell. Light adds charge density to the AMO structures in a cell.

    PHYSICS IS THE SCIENCE OF PROBABILITIES. BIOLOGY IS THE STORY OF THE IMPROBABLE AND BIOLOGY CAN ONLY MAKE SENSE FROM THE PERSPECTIVE THAT THE LIVING STATE IS ONLY PROBABLE ON EARTH USING REACTIONS UNDER SUNLIGHT WHICH ARE STATISTICALLY IMPROBABLE anywhere but on Earth.

    Knowing is just not enough. Understanding connections is critical. Stop being your own worse enemy. Stop looking outside for solutions when the wisdom you seek is buried with in you in how you organize matter in your cells with sunlight.
     
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  9. Jack Kruse

    Jack Kruse Administrator

    When light hits water it charge separates into electrons & protons. This means light brings liquid water closer to its ionization level. The water is physically changed to coherent domains. The interaction of light with liquid water generates quantum coherent domains in which the water molecules oscillate between the ground state and an excited state close to the ionizing potential of water.
    Quantum coherence in water refers to the ability of a quantum state to maintain its entanglement and superposition in the face of interactions and the effects of thermalization = added heat. When we add heat to a system it generates entropy = disorder = disease state. With quantum coherence, the development of entropy can be delayed and suspended for long periods of time.
    Mammals keep their body temperature relatively constant despite important changes in their metabolic rate. humans are really experts at this because of the high rate of metabolism and heat generation of their expanded brain tissues.

    Hydrogen acts like a gaseous neurotransmitter in cells. The gaseous neuro mediators are critical in thermoregulation, under the conditions of euthermia and anapyrexia. Data is now consistent with the notion that both NO and CO, acting in the CNS (intracerebroventricular approach), do participate in thermoregulation, NO decreasing body temperature (cooling thermogenesis), and CO increasing heat production. Hydrogen is transformed in photosynthesis and metabolism in life to create heat. Its movement in cells is a problem that water inside cells rectifies.

    Firstly, a large amount of heat is generated by converting the kinetic energy of the fast-flowing hydrogen into internal energy during motion. So inside cells, the half-life of hydrogen must be very small and controlled. Light and water do this in cells. Secondly, the compression of hydrogen in a delivery tank leads to the temperature rise, which is the most important factor leading to the temperature rise. The third is the negative Joule-Thomson effect of hydrogen, in which the flow through the throttle (ATPase) produces a sudden change in pressure that causes a temperature change. The electric and magnetic field generated in mitochondrial control this effect. At room temperature, most gases cool slightly during throttling. That is not true with hydrogen. This is why cytochrome c oxidase controls water production, NO action, and the flow of H+ linked to ATP creation. Sunlight, via NO release, controls thermoregulation for cells to maintain quantum coherence for long periods of time.

    Quantum coherence in water is said to exist when bond angles in hydrogen networks in liquid water are physically changed.
    The terms hydrogen ion H+ and proton, p or p+, are used synonymously in chemistry. It turns out the effect is massively important in the microbiome of the gut. This is critical in mental illness and autoimmunity states. Both diseases are born when there is a reduced ability or no ability to create hydrogen protons from splitting water. In other words, the microbiome needs quantum coherence to keep these disease phenotypes at bay.
    The intestinal microbiota produces up to 1L a day of hydrogen, but the gut does not use hydrogen gas the way entrepreneurs have designed machines to make hydrogen gas available for use. The methods of transformation matter. Cells have mastered this transformation using photosynthetic methods.
    The administration of hydrogen gas into the gut is a quantum complex. In lab experiments, it is aggravated by its very short biological half-life and low saturation point of 0.8 mM.

    Yesterday during my tour in St. Louis I gave a talk about how light and molecular H2 emissions from the microbiome control inflammation in the gut. This was an update on the talk I gave in Manilla in 2015. I was able to show them two devices we are working on using light, water, and H2 (with engineers) and how to treat the gut microbiome and autoimmune disease using the quantum biologic principles mentioned above. These are coherence-extending devices for those who are solar deficient or afflicted by too much nnEMF in their environment. Needless to say, the physicians were shocked at the scientific scale of science I am headed to these days.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680337/#B65
     
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  10. Jack Kruse

    Jack Kruse Administrator

    CLOCK and BMAL1 are positive regulators of circadian gene expression, and PER and CRY are the NEGATIVE FEEDBACK LOOP regulators that operate under day and night cycles. These are the positive and negative feedback arms of the circadian mechanism. So many different cancers are linked to a break in one side of these coupled cycles

    Epigenetic mechanisms are crucial mediators of environmental factors that modulate rhythmic gene expression. These vast changes in the epigenetic state alter dynamically over the day-night cycle. Circadian transcription and rhythmic chromatin modifications together regulate oscillations in gene expression. Rhythmic histone acetylation (H3K9, H3K14) was demonstrated on the promoter regions of CCGs, connecting histone acetyltransferase (HAT) p300 and the intrinsic CLOCK HAT activity. The latter was counteracted by the NAD(+)-dependent deacetylase sirtuin 1 (SIRT1) that adjusts the circadian acetylation of histones and non-histones. SIRT1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins.

    Mammalian sirtuins are found in numerous compartments within the cell (Table 1). SIRT1, -6, and -7 are found predominantly in the nucleus; SIRT3–5 reside in mitochondria, and SIRT2 is primarily cytoplasmic.

    When you do this due diligence you find out HMEC-1 transcriptional or translational analyses with a PER2 or HIF-1AKD revealed PER2-HIF1A-dependent regulation of SIRT3 does occur in all mammals under hypoxic conditions.
    Cellular stress activates SIRT3 and when this happens NAD+ drops in the cell.

    Most biochemists also don't seem to know how water is added to TCA intermediates to get into RNA and DNA. When the net negative charge is decreased in cells due to a lack of redox it implies a diminished ability to create coherent domains in cell water because mitochondria cannot make water well via the TCA cycling rate.
    Because of the atomic organization of cells (AMO physics) in health, there is always energy available within the system. In illness, this ability is diminished or lost. The energy derived from the sun is stored coherently, and ready for use, over all space-time domains. Mitochondrial water production is critical in the blueprint.

    As redox drops the net negative charge in a cell drops water creation drops. DHA'electron density is lost and this is why the cell can no longer store light energy in an illness state. As a result of these sequential changes, when a net negative charge is lost The hydrogen isotope type becomes the catalytic controller for succinate and fumarate in the TCA cycle. Nature requires that hydrogen proton flow must be made of light hydrogen isotope if the cycle is to move forward to reduce oxygen.

    Enzymes speed up chemical reactions in organisms by a factor of 10^10 to 10^23, but they cannot do it without water. They need light hydrogen protons to pull it off. Most people do not realize that a lack of water or dehydration ruins enzyme kinetics in cells (TCA cycle). They also fail to realize that the mitochondrial matrix creates a special type of water that works ideally with enzymes. The water is created by sunlight. Sunlight has a specific prescription to make the right type of water. Most other EMFs outside the visible spectrum do not allow mitochondria to create water. In fact, blue light and Xrays, for example, dehydrate cells. So EMFs are not all created equal when it comes to water. These nuances with EMFs and water are still hardly recognized in the conventional centralized biochemical community.


    When it moves the other way, bad things called diseases manifest. Why is light hydrogen critical in biology? Hydrogen bonds form between water molecules, giving rise to supramolecular aggregates/clusters/coherent domains. Enzyme kinetics is linked to hydrogen movements in them. They must be light hydrogen and they must be well hydrated to work because they rely on proton movements. This is how polymorphisms (SNPs) really are altered in us. The clustering of water leads to a cooperative phenomenon, which means that forming one hydrogen immediately favors the formation of several other hydrogen bonds, and vice versa, breaking one bond leads to breaking up a whole cluster. Thus clusters are dynamic flickering networks with lifetimes of 10^- 11 to 10^-10 seconds. SunLight changes those hydrogen bonding networks by moving charges around.

    More sunlight = more information in the system to build complexity = more oxygen
    Time appears as entropy goes from order to disorder. When entropy is controlled by a dissipative system, time can appear to be illusory.
    This means that the less information you have about a data set in a cell, the higher its entropy must be in the system. Cells limit entropy by controlling their atomic arrangements. In precise terms, entropy is a measure of the number of possible atomic arrangements that a system of particles can be in. This is important in understanding how Nature engineered our biological clock gene to work.

    Remember that stored energy in HEALTHY cells is coherent energy. The organism is, therefore, a highly coherent domain possessing a full range of coherence times and coherence volumes of energy storage. This keeps it far from equilibrium and makes it a highly dissipative system of organization to control entropy.

    Reminder: Cellular organization is the key to precision optical signaling. Life is all about optimizing AMO physics INSIDE OF CELLS. It transforms energy from the environment to do this. Modern physics now has proven that energy and information are equivalent in physics. Landauer's Principle of 1961 & Shannon's 1948 work was critical in making this linkage. Modern quantum biology has experimentally proven that energy is trapped directly at the electronic level in cells. Energy is stored not only as vibrational and electronic bond energies in biochemicals, but also in the structure of the system: its enzyme kinetics, membranes, and in gradients, fields and flow patterns, compartments, organelles, cell water, and tissues. All this in turn enables organisms to mobilize their energies coherently at any time it is needed and hence make available the entire spectrum of stored energies for physiological work. It is energy on demand by atomic design.


    Biochemistry doesn't know about the effects of red and NIR light on nitric oxide (NO) at cytochrome c oxidase in water creation or the ATPase spin rate in helping to drive the ECT and the TCA forward either. Few realize the spin rate is quantized to the amount of oxygen a mitochondrion needs in this process. Oxygen levels are linked to PER2 and HIF-1alpha. Sunlight creates oxygen via photosynthesis. The addition of UV-A light back to your system makes the forward progress of water creation more likely too. This is why cytochrome 1 (NADH/NAD+) is a fluorophore chromophore (aromatic amino acids spectra). It absorbs light best from foods and blood sources at 340nm. Fumerase's main function in the TCA cycle is to add water to TCA intermediates aconitase and citrate synthetase. The TCA cycle proceeds forward in doing when UV and IR light and large coherent domains are present in the matrix. The TCA cycle occurs in the mitochondrial matrix exclusively.

    SIRT3 controls energy demand during stress conditions (hypoxia/pseudohypoxia) such as fasting and exercise as well as metabolism through the deacetylation and acetylation of mitochondrial enzymes. SIRT3 is well known for its ability to eliminate reactive oxygen species and to prevent the development of cancerous cells or apoptosis.

    https://m.facebook.com/drjackkruse/...nadh-ratio-nad-drops-in-peop/968174293246925/
     
  11. Jack Kruse

    Jack Kruse Administrator

    What does disease look like to the decentralized clinician?

    Loss of clock gene feed back loops = Pseudohypoxia = low O2 = Low NAD+/NADH ratio = NAD+ drops in people with blue light exposure = NADH is the source of electrons in mitochondria = low NAD+ = missing electrons = missing mitochondrial water = net positive charge in mitochondria = less piezoelectric current from mitochondria to system = elevated ubiquitin rates = low levels of electrons = too much deuterium in the matrix = matrix is more dense and less compressive due to KIE = less piezoelectric squeeze = lowed DC electric current = lowered electron density in tissues = results in breakage of Bazan loops = lowered DHA concentrations in cells = low EZ size in cell water = dehydration = higher positive charges (protons) in proteins making them less hydrophilic = low intracellular pH = low redox potential = cell and mitochondrial swelling (cytochrome c release) = decreased mitochondrial water production = altered CO2 in blood = lowered Vitamin D levels in gut = lowered magnetic and electric fields in mitochondria = low ATP levels = a lot of carbs and protein electrons on ECT = altered NO, melatonin, serotonin and dopamine levels in the retina and frontal lobes = NT release tied to calcium efflux = calcium controls voltage-gated channels, deuterium concentration in the matrix, NMDA, and glutamate excitotoxicity = low DC electric current = low tissue DHA = altered perceptions of reality and depression/anxiety and just about any other disease you want to understand.

    Ideas, like these above, are like rabbits. You get a couple of them together and learn how to handle them, and pretty soon you have a dozen to change medicine to a DeMed platform.

    EVERY cell houses 4 light-activated genes — cryptochrome, Period, CLOCK, and BMAL — that keep time. When you mess with circadian signaling with things like artificial blue light, BMAL1 causes your mitochondria to swell and you begin to develop insulin resistance. Restore proper BMAL1 activity and you restore proper cellular function. Restore proper BMAL1 activity and you restore proper cellular function." So would abnormal circadian rhythmicity = poor redox = mitochondrial senescence because http://www.jbc.org/content/280/22/21061.full
     
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  12. Jack Kruse

    Jack Kruse Administrator

    Electromagnetic fields can activate voltage-gated calcium channels (VGCCs) via molecular resonance in the plasma membrane of cells. When electromagnetic fields activate these channels, large amounts of intracellular calcium (Ca2+) are produced. The amount produced is subject to the wave physics of the emitted light wave from the point source. If the wave is polarized this also changes the calcium efflux and its ionic resonance. Calcium is the key secondary messenger in cells for these antigens on the surface and they interact and react with RNS species like peroxynitrite (RNS radical).
    This excess calcium within the cells produces a chain of free radical chemical reactions from the mitochondria which change the physiology of the cell at a femtosecond basis. This leads to the production of a VARYING free radical signal that causes organizational chaos in the cell. That chaos is manifested by the disruption of the incident EMF that excites and activates the voltage-gated channels in the cell. A highly variable incident EMF with produce a highly variable ROS/RNS mitochondrial signal and this results in unpredictable biochemistry in the cell. This is associated with the production of chronic oxidative stressor chemicals in the living system that cannot be buffered by the normal quenching chemicals in cells. All of this results from an environment that produces an altered electric and magnetic field around an animal/human.
    The chaotic free radical signal is capable of culminating in DNA damage and or the change in the plasma membrane to lead to pathologic symptoms and eventual disease.
    The calcium efflux causes excess calcium directly in and around the cell and in its local environment. So with respect to RBCs, it also means that this effect of electric and magnetic fields will also affect the surface of the blood vessels. Peroxiredoxins are the key peripheral circadian controller that removes CpG Island from the fragmented DNA and mtDNA that enter the blood when nnEMF is destroying cellular biology. Tight control of RBC circadian cycles links RBC antigen clearance to the innate immune system via C4. RBCs become more permeable to toxins in this case and as a result, the RBC ages faster and more antigens pass through the circulatory system. This is really what happens in all mold and biotoxin diseases. It is not the mold or toxin that is critical in this case, it is the REMOVAL of the nnEMF field that is critical to get right. Most clinicians out there never get this advice to their patients or the public.
    All of these mechanisms of nnEMF field exposure alter melanopsin biology in the blood and arteries to a chaotic release of nitric oxide (NO) within cells and in arteries to cause disease when it occurs chronically and affects mitochondrial function when other frequencies of sunlight are subtracted from this photic dance.
    The increase of nitric oxide is a chameleon event in the blood plasma. Endothelial nitric oxide synthetase has a quantum superposition effect on sulfur atoms in the skin, arteries, blood, and gut to protect us from dangerous nitrogenous groups in these antigens.
    This means that any pulsed or polarized non-native man-made electromagnetic signal can have a variable non-linear effect on sulfation and nitrosylation pathways in any of these organs. I covered this last night in my Feb 2019 webinar Q & A.
    It can result in therapeutic effects or detrimental effects in the blood plasma depending upon the nnEMF stimulus. This will lead to highly variable chaotic mitochondrial energy flux and fidelity signal dynamics. This is very damaging to the matrix and directly affects what biochemistry can or cannot occur. This is one reason why non-thermal electromagnetic fields (PEMF) are increasingly used in medical therapies, but they are being used without any proper understanding of how they truly operate.
    Today the sellers and purveyors of these devices think and believe that their RF/microwaves effect is always beneficial therapeutically in a wildly variable world of surrounding nnEMF. THIS IS PURE FALLACY AND MARKETiNG BuLLSHIT.
    Moreover, they fail to realize that this eNOS switch in cells is very sensitive to any variable PEMF RF pulse. This is why PEMF devices need to be strictly avoided in a 5G world. Yes, that includes all the Oura rings and PEMF devices pushed by BEMER and Dr. Havas based on the latest NTP study on RF radiations.
    For example, if one is in an environment that fosters chronic nitric oxide release this means there will be a relative lack of sulfation of the skin, arteries, and gut, and RBC and this would favor the activation of the reactive nitrogen species of chemicals. This is particularly devasting to the microbiome because NO and H2S work in unison to control the constitution of the microbiome.
    In fact, we now know that nitric oxide can also interact with the superoxide pulse (OO-) created in cytochrome one (NAD+/NADH) from altered mitochondrial function to create peroxynitrite (ONOO-) to do further damage. This is why people with gut and microbiome conditions relapse so often in toxic nnEMF environments loaded with blue light. Most doctors are not sophisticated enough yet to understand that things like SIBO and adrenal fatigue are adaptative and not pathologic symptoms tied to altered and highly variable EMF fields that their patients live in.
    It has been found that when peroxynitrite breaks down, it creates reactive free radicals and oxidative stress within cells and this likely leads to many of the symptoms of CV and neurodegeneration on longer timescales. In this way, both atherosclerosis, CV, and neurodegeneration can be thought severe chronic adaptive mechanisms employed by cells that have developed an innate immune allergy to nnEMF.
     
  13. Jack Kruse

    Jack Kruse Administrator

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  14. Jack Kruse

    Jack Kruse Administrator

    REDOX 101 LESSON: The last 30 minutes of this video has a ton of information about redox power in cell biology. The topic of this podcast was fluoride but a lot of the information was linked to mitochondrial redox power loss.


    For example:
    1. As redox drops the net negative charge in a cell drops and water creation in the mitochondrial matrix drops. Fluoride lowers your redox power because it destroys the dielectric constant of water inside of you. DHA has a massive pi electron cloud. Electrons are excited by sunlight photons. DHA's electron density is lost and this is why the cell can no longer store light energy in an illness state. As a result of these sequential changes, when a net negative charge is lost the hydrogen isotope type becomes like a catalytic controller for succinate and fumarate in the TCA cycle. Light hydrogen builds the right water from TCAP metabolism. When the net negative charge in a cell is lost, water has a higher deuterium content in it. This increases the atomic mass of water and it hinders proton tunneling in enzymes and between DNA and water that surrounds it. Nature requires that hydrogen proton flow in cell water must be made of light hydrogen isotope if the cycle is to move forward to reduce oxygen. Deuterium slows the proton flow via its higher kinetic isotope effect in cell water. As a consequence, fluoride use also slows the cyclic rate of the TCA cycle which is why redox power is lost.

    2. Deuterium's isotope effect causes DNA to be a more heavy and more sticky mess because the deuterium content increases bonding energies between atoms. This is a huge deal in enzymes. Enzymes are catalysts that speed things up in cells by facilitating atomic motions. DNA needs parts of it to be deuterium free for faster action and there are other places where deuterium is useful in the DNA backbone to stop enzymes from copying the nuclear code. Deuterium will not let go of enzymes to do their job in the matrix!!!! This means we lose the ability to recycle DDW water!!

    It also means that all cell membranes inside the cell and organelles are going to be loaded with deuterium too. They become quite sticky as a result. This affects the lipid rafts where DHA controls the lipid cytosocial architecture in how they operate with incident light frequencies. Why? NADPH is also the main reducing element in making cell membrane fats!!!!!

    The deuterium content ruins optical signaling with ELF-UV because deuterium massively increases bonding energies anywhere it is located in a CELL!!!!! So you might begin to see why limiting proton motions is a BIG DEAL in a cell!

    3. It also explains why cancer states are associated with more ELF-UV light release when our deuterium fractions are up. More deuterium = more mass = more light energy is needed to break bonds to move things fast inside a cell. The cell knows it needs more light power to overcome the bonding strength of deuterium in the cell membranes. This is why sick eukaryotic cells release more light in disease states. Deuterium also makes chromatin sticky because of its high kinetic isotope effect and it blocks the normal functioning of unwinding DNA for coding and protein translation. It ruins everything a cell needs to do in run through the cell cycle. This is why the growth switch stays ON and why some forms of cancer are more likely to manifest.

    4. So how does deuterium get into DNA? When your circadian mechanism is broken fluoride can cause way more damage. Fluoride competes with oxygen due to its high electronegativity. It effectively steals electrons from oxygen. Electrons are excited by photons. With fewer electrons available less light energy can be stored inside a cell = poor redox power. This lowers mitochondrial respiration which lowers the amount of water a mitochondrion can make. hypoxia = a lack of oxygen. This stimulates HIF 1- alpha. HIF 1- alpha is an analog of the PER2 clock gene in mammals. When oxygen drops, cells stop using protons from TCA intermediates for their hydrogen source for fats and water that they create.

    5. Cells also stop using TCA for hydrogen harvesting when they have to use the serine oxidation glycine cleavage system. The serine glycine cleavage system is a backup system for H+ harvesting. It is made up of an H-protein, a protein that carries the amino-methyl intermediate and then hydrogen through the prosthetic lipoyl moiety, and an L-protein, a common lipo-amide dehydrogenase-like lignoceric acid. Lignoceric acid is a fatty acid that makes up the lipid rafts of all eukaryotic cell membranes including the nuclear membrane. It controls the size and shape of the nuclear membranes!!!! Dysfunction at this level leads to chromosomal problems at mitosis because they are more sticky and we get something called aneuploidy. This is a precancerous step in a cell. And here we are back to the link to size and thermodynamics. Anything that is getting larger in the universe is losing energy. Things that can maintain their size and shape are doing so because they are controlling the arrangement of atoms in cells to store energy.

    6. Enzymes speed up chemical reactions in organisms by a factor of 10^10 to 10^23, but they cannot do it without water made in the mitochondria matrix. They need light hydrogen protons to pull them off because they move rapidly and do not have a high kinetic isotope effect.

    Most people do not realize that a lack of water/dehydration ruins enzyme kinetics in cells (TCA cycle). They also fail to realize that the mitochondrial matrix creates a special type of water that works ideally with enzymes. The water is created by sunlight. Sunlight has a specific prescription to make the right type of water. Most other EMFs outside the visible spectrum do not allow mitochondria to create cell water.

    In fact, blue light and Xrays, for example, dehydrate cells. So EMFs are not all created equal when it comes to water. These nuances with EMFs and water are still hardly recognized in the conventional centralized biochemical community.


    When it moves the other way, bad things called diseases manifest. Why is light hydrogen critical in biology? Hydrogen bonds form between water molecules, giving rise to supramolecular aggregates/clusters/coherent domains. Enzyme kinetics is linked to hydrogen movements in them. They must be light hydrogen and they must be well hydrated to work because they rely on proton movements. This is how polymorphisms (SNPs) really are altered in us. The clustering of water leads to a cooperative phenomenon, which means that forming one hydrogen immediately favors the formation of several other hydrogen bonds, and vice versa, breaking one bond leads to breaking up a whole cluster. Thus clusters are dynamic flickering networks with lifetimes of 10^- 11 to 10^-10 seconds. Sunlight changes those hydrogen bonding networks by moving charges around at very rapid rates. When the rate slows entropy in the cell rises and diseases result.

    The cellular organization is the key to precision optical signaling. Life is all about optimizing AMO physics INSIDE OF CELLS. It transforms energy from the environment to do this. Modern quantum biology has experimentally proven that energy is trapped directly at the electronic level in cells. Energy is stored not only as vibrational and electronic bond energies in biochemicals, but also in the structure of the system: its enzyme kinetics, membranes, and in gradients, fields and flow patterns, compartments, organelles, cell water, and tissues. All this in turn enables organisms to mobilize their energies coherently at any time it is needed and hence make available the entire spectrum of stored energies for physiological work. It is energy on demand by atomic design.
     
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  15. Jack Kruse

    Jack Kruse Administrator

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  16. Jack Kruse

    Jack Kruse Administrator

    So what did I say to @RickRubin and @hubermanlab anyhow?
    https://www.patreon.com/posts/quantum-30-grass-79808941

    The focus of this QE series has been to ask better questions than the answers the experts have given us to solve the puzzle of human evolution. I am going to share with you the evidence I have amassed in my brain over the last 20 years when I had my epiphany at the foot of Michelangelo's David. I recounted that day to Mr. Rick Rubin and Dr. Andrew Huberman this past weekend without a lot of detail I never discussed publically. After the last two years, the time is now to unleash these details. I think the public is ready to understand my perspective fully now.

    That one moment 20 years ago has allowed me to think about how human disease may be the evolutionary building blocks of our homo species. If my instincts are correct, this has huge implications for how we should be treating modern humans. How we do things will change dramatically in future decentralized healthcare. I laid this idea out last weekend in detail for all of you to hear. I hope you enjoy that discussion and this current series. I think this work is worth 5 bucks a month and I hope you do too. Good medicine does not have to be expensive. Please ask people to join us in changing the world. All it takes is a thought to change the world. That thought is created when sunlight hits melanin in your eye before it ever gets to your brain. Where I am going to take you might shock some of you.
     
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  17. Jack Kruse

    Jack Kruse Administrator

    The beginner always begins with light, water, and magnetism for brain expansion.

    How do you change your thoughts? You need to allow the sun and water to interact in your cells. Then new thoughts manifest via non-linear optics.

    How?

    https://threadreaderapp.com/thread/1634660123456012291.html
     
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