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Discussion in 'Mitochondrial Rx' started by Jack Kruse, Jun 6, 2022.

  1. Jack Kruse

    Jack Kruse Administrator

  2. What I find interesting is the angel the cone receptors will turn.


    Cone mitochondria in dorsal GS retina. Left: Cone photoreceptor anatomy in an immunolabeled vertical section. The arrow indicates the junction between the IS and cell body. Right: Top-down flat-mount view of TMRE-labeled mitochondria in live photoreceptors. RCVRN, recoverin.


    (B) Conceptual illustration of angle-dependent concentration of light upon the cone OS.

    Thus, according to our optical model of mitochondria, light arriving along this axis of alignment will be maximally concentrated onto OSs; however, light entering instead at a small angle from this axis will partially miss the OS

    (C) Diagram of the SCE and directionality. Angular dependence of light focusing shown here in GS is overlaid upon directionality tuning curves based on measurements in human SCE and turtle cone light responses.


    (E) Directionality of simulated light concentration in the OSR by GS cones. Left: Example simulations with models tilted by the indicated angles. Overlay shows the simulations rotated in register with one another in different colors for comparison. Graph shows the directionality fit analysis [compare to (C)] across simulations for all cone models (three angles per cone model).

    Dr. @Jack Kruse - When you can make the time, please read
    I would appreciate your feedback on my "quantum" explanation for the behavior of choroid plexus' cells.
    Last edited: Jun 6, 2022

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