1. Registering for the Forum

    We require a human profile pic upon registration on this forum.

    After registration is submitted, you will receive a confirmation email, which should contain a link to confirm your intent to register for the forum. At this point, you will not yet be registered on the forum.

    Our Support staff will manually approve your account within 24 hours, and you will get a notification. This is to prevent the many spam account signups which we receive on a daily basis.

    If you have any problems completing this registration, please email support@jackkruse.com and we will assist you.

Melatonin produced in the lungs prevents infection by novel coronavirus

Discussion in 'Educating Doctors' started by DrEttinger, Jan 30, 2021.

  1. DrEttinger

    DrEttinger Choice, the only thing we control

    Melatonin does WAY more than just help us to transition from wakefulness to sleep. Research has shown that mitochondrial produced melatonin is one of our most potent antioxidants as well as modulating immune responses by both directly crossing the mitochondrial membrane as well as working inside. Inside the mitochondria, it can act to protect the mitochondria from oxidative damage (Think heart [30% of a cardiomyocyte is mitochondria], brain, liver, and muscle). Educate yourself on the mitochondria and (Google) "techniques to stimulate mitochondrial biogenesis." You're only as good as your mitochondria.

    The research from the article showed that melatonin produced IN THE LUNG (Not taken as a supplement and not released by the pineal gland) acts as a barrier against SARS-CoV-2, preventing the virus from entering the epithelium, activating the immune system, and triggering the production of antibodies. This is produced in the mitochondria.

    Air pollution also induces the production of melatonin and other molecules by the macrophages, engulfing the particulate matter in the air breathed in and stimulating mucous formation, coughing, and expectoration to expel the particles from the respiratory tract.

    Additional data to go with the first article -

    Mitochondrial cytochrome c oxidase is not the primary acceptor for near-infrared light—it is mitochondrial bound water: the principles of low-level light therapy

    There is substantial evidence that various wavelengths of light, including R-NIR delivered by lasers or LEDs, are instrumental in upregulating mitochondrial ATP levels. Conflicting data cast serious doubt on the validity of the concept that CCO is the primary photoreceptor for R-NIR light being causal for the ATP upregulation. At the same time, there is conclusive evidence that both ATP upregulation and cell proliferation by R-NIR light occurs via the interaction of photons with intracellular IWL.

    Yours in good health,

    Dr. Ettinger
  2. Last edited: Jan 30, 2021
    Josie Thomson and JanSz like this.
  3. I love human studies https://academic.oup.com/biomedgerontology/article/75/9/e49/5863431

    Attached Files:

    JanSz likes this.
  4. JanSz likes this.
  5. 670 nm full body exposure for 20 minutes each night for 14 days increased peak circulatory melatonin levels compare to control. https://www.melatonin-research.net/index.php/MR/article/view/19/208
    Subcellular melatonin has been shown to be produced in orders of magnitude higher quantities than the pineal gland produces.

    Circulatory melatonin is stimulated by the absence of light.
    However, subcellular melatonin may be stimulated by the presence of light.

    Melanin rich individual have much different absorption profiles in their skin but still receive significant levels of exposure even 8 cm into the body.

    So what has @Jack Kruse written about melanin and building your solar callus? https://www.facebook.com/drjackkrus...ood-and-sunlight-critical-t/2156289451102064/

    Astaxanthin helps manage your melanin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073124/
    Last edited: Jan 30, 2021
    Josie Thomson, Penny and JanSz like this.
  6. Pulsed Led's Light at 650 nm (Red) Promote and at 470 nm (Blue) Suppress Melatonin's Secretion https://www.researchgate.net/publication/273948669_Pulsed_Led's_Light_at_650_nm_Promote_and_at_470_nm_Suppress_Melatonin's_Secretion

    Red light increases activity of mitochondrial cytochrome c oxidase
    However, blue light depress or suppress mitochondrial cytochrome c oxidase
    The oxygen demands of photoreceptor cells are 3-4 times greater than those of other retinal and central nervous system neurons, and the estimates of the rate of oxidative metabolism in photoreceptor cells are among the highest in the human body. The cluster of mitochondria in the inner segment accounts for the intense oxidative metabolism of glucose. https://www.hindawi.com/journals/omcl/2019/6435364/

    Blue LED (460 nm) damage retinal photoreceptors https://www.sciencedirect.com/science/article/abs/pii/S0891584915001586?via=ihub

    Question: Why is blue light damaging?
    Because it is so stimulating specifically for improving cognitive brain function -> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865352/
    Last edited: Jan 30, 2021
    Michael CULLEN and JanSz like this.

Share This Page