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Low Cortisol Levels

Discussion in 'Optimal Labs' started by Eddie Garza, Apr 29, 2015.

  1. nicld

    nicld Gold

    I LOVE Disturbed's version. David signs with such passion especially when he sings the line "and people bowed and prayed to the the neon god they made." Their whole new album is pretty good.
     
  2. JanSz

    JanSz Gold

    https://www.facebook.com/groups/872967099382852/1121819717830921/

    What I have found in my career in surgery and bio-hacks is the only place where your dreams becomes impossible is because of fears within your own thinking. Luck is nothing but statistical likelihood. Fortune sides with him who dares to act and innovate. The more you try things in life, the luckier you seemingly become. Medicine has taught me the only safe thing humans can really bank on is taking a chance that sunlight might be a Rx for optimal.
     
    Phosphene likes this.
  3. KalosKaiAgathos

    KalosKaiAgathos New Member

    I've been testing the Osram Ultra Vitalux. It's ultra to say the least. I can stand in front of it (30-50cm distance) for about a few minutes before my skin turns red. In comparison, I can stand in front of the Solar Glo easily now, and can apply it from a very short distance from the skin without burning.

    I'll report back on both the Vitalux and the NIR bulbs. The NIR bulbs are amazing, as my skin softness has reached new levels!
     
    seanb4 likes this.
  4. JanSz

    JanSz Gold

    Last edited: Feb 3, 2016
  5. JanSz

    JanSz Gold

    http://www.westonaprice.org/our-blogs/cmasterjohn/vitamin-d-problems-with-the-latitude-hypothesis/

    [​IMG]

    Vitamin D — Problems With the Latitude Hypothesis
    Posted on December 24, 2010 by Christopher Masterjohn
    - See more at: http://www.westonaprice.org/our-blo...ude-hypothesis/#sthash.PpgxOb5I.bTZN8P0B.dpuf

    ==============================

    I recently pointed out in my post “Are Some People Pushing Their Vitamin D Too High?” that there is very little scientific evidence that
    we need 25(OH)D levels higher than 30-35 ng/mL (75-88 nmol/L).
    Even the evidence for 30-35 ng/mL is primarily observational, meaning that we have very strong reasons for promoting the hypothesis, but no solid confirmation.

    Research that has emerged since 2006 has threatened to turn the “latitude hypothesis” of vitamin D on its head.
    - See more at: http://www.westonaprice.org/our-blo...ude-hypothesis/#sthash.PpgxOb5I.bTZN8P0B.dpuf

    ===============================
    @Jack Kruse

    @Dia

    ////////
     
  6. JanSz

    JanSz Gold

    https://forum.jackkruse.com/index.php?threads/apps-that-can-be-used-to-listen-to-the-blogs.17361/

    [ quote="Rubicon, post: 185911, member: 18225"]Typically I generally prefer listening to audiobooks vs reading text, and I wanted to share a method I've been using to listen to the blogs which involves using the app "Pocket":
    1. Download Pocket to your phone (Android) (iPhone)
    2. Login to Pocket and browse to the blog page you'd like to listen to. On mobile, you should have an option to "Share to Pocket". Alternatively, a method I use is to get the Pocket Chrome extension and save the blogs I want to listen do via desktop.
    3. Once you've saved some blog posts to Pocket, open the Pocket app and you'll see a list of saved blogs. You can now put your phone into airplane mode, view the the blogs, and select, "Listen (TTS)"
    4. Pocket will now read the blog to you in a computer voice using Text To Speech (TTS)
    In general the computer voice & pronunciation in the app is pretty good. I like to go for a 30-60 min walk as the app reads a blog to me.[ /quote]
     
    wildperoxin, kyrakitty and seanb4 like this.
  7. Jack Kruse

    Jack Kruse Administrator

  8. JanSz

    JanSz Gold

    Albedo is the fraction of solar energy (shortwave radiation) reflected from the Earth back into space. It is a measure of the reflectivity of the earth's surface. Ice, especially with snow on top of it, has a high albedo: most sunlight hitting the surface bounces back towards space.

    [​IMG]
    .......................................Incoming Solar Radiation=341.3 W m^(-2)

    .......................................................... Net absorbed=0.9 W m^(-2)

    http://tinyurl.com/htx3u8e

    .
     
    Last edited: Jan 11, 2016
  9. Calum

    Calum New Member

    the bulbs are so much cheaper in the US vs UK.. twice as cheap:(
     
    seanb4 likes this.
  10. JanSz

    JanSz Gold

    http://appliedergogenics.blogspot.com/2013/11/jfk-steroid-user-by-jerry-brainum.html
    John F Kennedy's medication stack.


    Friday, November 22, 2013
    JFK: steroid user by Jerry Brainum



    The 1960 presidential election was considered one of the closer elections in American history. Many historians say that the turning point came on September 26, 1960, with the advent of the first televised presidential debates. John F.Kennedy was the democratic candidate, a United States Senator from Massachusetts. Incumbent vice-president Richard Nixon represented the Republican party. Both men presented clear and cogent arguments and brought up important issues. If you went by content alone, you would have to declare a tie, with no clear winner. However, those debates turned the tide for Kennedy. It wasn't anything particular that he said, but rather how he looked that made the difference. Kennedy appeared tan and rested, while his opponent Nixon looked pale and sweaty; in fact, he was sick. Nixon had refused make-up, and the cameras caught every bead of sweat and bags under his eyes. In contrast, Kennedy seemed to present a picture of youthful vigor and energy. In fact, nothing could be further from the truth. Nixon was by far the healthier of the two candidates.
    Kennedy had more personal medical issues that any United States president, before or since. The extent of his health problems became apparent with the complete release of his medical history eleven years ago. What Kennedy was afflicted with falls under the broad medical term of autoimmune polyendocrine syndrome, type-2 (APS-2). What this refers to is a failure of several endocrine organs, or organs that release hormones, caused by the body's immune system turning upon itself, and attacking those organs as if they were foreign disease organisms. The syndrome was initially described by Thomas Addison in 1849. The type-2 form that JFK had is characterized by a failure of his adrenal glands, along with a failure of the thyroid gland.
    Kennedy was known to suffer from Addison's disease, named after that same Dr.Thomas Addison, who first described it. With Addison's disease, the adrenal glands stop producing hormones. This aspect of Kennedy's health was kept secret for years, and the full disclosure only emerged with the publication of a book in 1976. There were signs of problems long before that, however. In September, 1947, JFK, then a U.S Congressman, collapsed while on a visit to England. A local doctor diagnosed Kennedy's illness as "adrenal crisis" and remarked to a friend of Kennedy "that young man doesn't have a year to live." Kennedy left for New York accompanied by a nurse, and was admitted to the Lahey clinic in Boston. The press was told that the reason for Kennedy's illness was a severe recurrence of the malaria he had contracted while serving in the Pacific during World War two.
    In reality, JFK was being treated at the Lahey Clinic by an endocrinologist, who gave JFK an early corticosteroid drug, namely desoxycorticosterone (DOCA). This was in pellet form, which was implanted in the skin of his thigh every three months. In 1950, oral cortisone became available, and Kennedy began ingesting 25 milligrams daily in addition to continuing the DOCA treatment. He had to do this because with the Addison's disease, he wasn't producing any cortisol, which is essential to life. He wasn't actually diagnosed with Addison's until September, 1947. When he first ran for congress in 1945, JFK weighed only 150 pounds at a height of 6-foot, and as the campaign went on, he was descibed as appearing "tired, hollow-eyed, and anemic" by his staff workers. Despite this, JFK seemed indefatigable, and won the election. But the day prior to the election, he had marched in the annual Bunker Hill parade, and at the end of the 5-mile walk, he collapsed. One aid said that he looked "yellow and blue, like a man having a heart attack."
    Back in 1940, when he was only 23, JFK was given a medical examination by a doctor, who told JFK's father than his son had hypotension, or very low blood pressure. This was an early sign of his adrenal failure.Kennedy's celebrated tan was also a manifestation of his adrenal failure. It was hardly a"healthy tan."
    In 1954, as a U.S Senator, JFK had back surgery to correct long standing pain that may have been caused by long term use of steroids (not anabolic steroids), which can cause bone resorption and thus weaken spinal bones. The doctors who operated on him had to take special precautions because of his Addison's disease, since JFK's body was incapable of handling stress. He survived the surgery, which was written up in a medical journal--without identifying the patient.JFK still suffered from back pain the rest of his life, and was wearing a back brace on the day of his assassination.That brace, which allowed him to keep his upper body erect, may also have inadvertently led to his death in Dallas on November 22, 1963. JFK's erect body and lack of flexibility allowed the second bullet that smashed into his skull to efficiently find its target. This was the bullet that blew the back of his skull off and proved fatal. Had he been able to move more without the brace, the bullet might have missed, and JFK would have survived.
    Kennedy's political opponents were aware of Kennedy's Addison disease, and tried to go public with the disclosure that JFK was in fact, a sick man. But his condition was covered up by Dr.Janet Travell, who later became the White House physician. In 1955, JFK was diagnosed as having hypothyroidism, or low thyroid output.During his presidencny, JFK took 25 micrograms of liothyronine, better known by its trade name of Cytomel, twice a day. Cytomel is a T3 thyroid drug, considered the fastest acting and most potent of thyroid medications. The diagnosis of both adrenal and thyroid failure is indicative of APS-2. Again, this stems from the body producing an immune reaction that attacks the adrenal and thyroid glands. At Kennedy's autopsy,it was noted that his adrenal glands had atrophied to the point of non-existence, which is indicative of severe Addison's disease. Half of those with APS-2 have relatives who also suffer from autoimmune disease. Kennedy's sister, Eunice, mother of Maria Schriver, also had Addison's disease, while Kennedy's son, JFK Jr, had Graves disease, which is characterized by excessive thyroid output, and is considered an autoimmune disease.
    Those who suffer from APS-2 show an incidence of hypergonadotropic hypogonadism of 4 to 9 percent. This could lead to infertility, which clearly wasn't the case with JFK, who sired four children, with two surviving infancy.However, the syndrome can also affect the gastrointestinal system, and JFK suffered from recurrent symptoms of intestinal cramping, diarrhea, and inability to gain weight for most of his life.
    A list of medications prescribed by Dr.Travell on
    October 12, 1961 for JFK consisted of the following:
    Vitamin C, 500 mgs, twice daily;
    hydrocortisone, 10 mgs daily;
    prednisone, 2.5 mgs, twice daily;
    methyltestosterone 10 mgs daily;
    25 mcg twice daily of Cytomel for thyroid;
    fludrocortisone, 0.1 mgs daily;
    diphenoxylate HCL and Atropine (Lomitol), 2 tablets as needed to treat diarrhea.
    Kennedy used testosterone daily during his entire presidency. He usually used
    10 mgs of the anabolic steroid, methyltestosterone, one of the only orally available anabolic steroids at that time, and sometimes boosted the dose to 25 milligrams.
    In 1962, his doctors put him on between 50 and 75 milligrams of testosterone aqueous suspension, an injection, for four days.
    He later began taking fluoxymesterone,another oral anabolic steroid available as Halotestin, at a dose of 5 to 10 milligrams.
    With Kennedy's autoimmune condition, it's possible that antibodies could attack the Leydig cells in the testes, where testosterone is synthesized. While JFK may have had this effect, it didn't destroy his fertility, as evidenced by his ability to produce children (with his wife's assistance). But the probable reason why Kennedy used testosterone preparations was to counter the catabolic effects on muscle produced by his necessary use of corticosteroid drugs, which are catabolic hormones, in that they produce muscle tissue loss. In addition, regular use of cortisol-based drugs can result in pituitary suppression of gonadal hormone output. In other words, using cortisol drugs can blunt the synthesis of testosterone in the body, necessitating an outside source of the hormone. Kennedy would often request higher doses of his testosterone or anabolic steroid drugs because they made him feel more alive and clear-headed, while reducing his ever-present feeling of fatigue. His inability to gain weight because of the Addisons also made testosterone drugs a useful option, since they allowed JFK to gain weight and improve his appearance. Before he used the drugs, he appeared gaunt and very skinny.He actually first started using testosterone when he ran for president in 1960, again to improve his appearance and sense of vigor, which it did.
    JFK also used vitamin B12 injections throughout his presidency. The APS-2 condition, because of adverse effects on the gastrointestinal system, often leads to a B12 deficiency, which JFK did have, hence the B12 injections.
    Just like a Hollywood facade, JFK wasn't the picture of youthful health and vigor that he appeared to be.But without his hormone treatments, including the corticosteroids he had to use to stay alive, and the testosterone preparations that made him look healthy despite his illness, history may well have not been the same.



    [​IMG]



    [​IMG]



    ©,2013 Jerry Brainum. Any reprinting in any type of media, including electronic and foreign is expressly prohibited.
    Please consider joining this blog by clicking on the blue "join this site" button to the right of this blog. This will ensure that new blogs continue to be published. It costs nothing, and takes only a few seconds. Thank you.
     
    seanb4 likes this.
  11. JanSz

    JanSz Gold

    @Jack Kruse


    Most men using testosterone (without HCG)
    see their LH & FSH depressed, often to nothing.
    The testicles disappear.
    This happened to me when I first started using Androgel in 2000.

    No FSH, no testicles, no sperm.
    ---------------------------------------------
    JFK first started using testosterone when he ran for president in 1960

    Date o birth of his children.
    http://www.sptimes.com/News/111199/JFK/family-tree.shtml

    John Fitzgerald Kennedy, born May 29, 1917; 35th U.S. president.
    Married Jacqueline Bouvier on Sept. 12, 1953.
    They had three children.
    =====================================

    Caroline Bouvier Kennedy, born Nov. 27, 1957.

    John Fitzgerald Kennedy Jr., born Nov. 25, 1960.

    Patrick Bouvier Kennedy, born Aug. 7, 1963; died Aug. 9, 1963
    =======================================
    He actually first started using testosterone when he ran for president in 1960
    =======================================
     
    Last edited: Jan 12, 2016
  12. KalosKaiAgathos

    KalosKaiAgathos New Member

    Some n=1 case study updates.

    NIR sauna by itself, with 15-30 minute sessions: Good
    NIR sauna with 30+ minute sessions: Less good
    Viatalux by itself: Good
    20-25 minutes NIR sauna with the first 5-8 minutes vitalux: Amazing!

    The strange thing is that only with the combination of the two, I get UV skin reddening. The NIR causes reddening by itself by the increased blood flow, but the UV reddening is different. When I use the Vitalux by itself (without the NIR), it does not result in the typical UV reddening to any large extent.

    Quick Edit: I apply them in the cold to maximize the effects
     
    Last edited: Jan 21, 2016
    seanb4 and lilreddgirl like this.
  13. Jack Kruse

    Jack Kruse Administrator

    good stuff Jansz
     
    JanSz likes this.
  14. JanSz

    JanSz Gold

    'Frozen' Man Revived From the Brink of Death After Being Found in the Snow With No Pulse
    http://abcnews.go.com/Health/frozen-man-revived-brink-death-found-snow-pulse/story?id=36380318

    'Frozen' Man Revived From the Brink of Death
    A Pennsylvania man's tale of survival is drawing attention to the dangers of cold weather exposure after a walk home in subzero temperatures left him unconscious, with no pulse when he was found in the snow the following day.

    Justin Smith, 26, was walking home in below freezing temperatures after having a few beers with friends last winter when he blacked out, according to the Lehigh Valley Health Network. The college student was in the snow for hours as temperatures plunged to 4 degrees Fahrenheit below zero.

    He wasn't found until the next morning, when his father Don Smith saw his son lying by the road.

    "He was blue his face, he was lifeless. I checked for a pulse, I checked for a heartbeat, there was nothing," Don Smith told ABC affiliate WNEP.

    Nearly a year after the ordeal, Justin Smith was finally healthy enough to thank his doctors in person at a news conference on Monday. His doctors said Smith's incredible tale of survival may affect how they treat other hypothermic patients in the future.

    Boy Survived Over 1 Hour Without Pulse


    Boy Lives After 25 Minutes Underwater


    Boy Born Without Most of His Skull Beats the Odds to Survive


    When Don Smith called paramedics after finding his son unconscious in the snow, they did not give up on the student. They started CPR with chest compressions.

    Dr. Gerald Coleman, an emergency medicine physician at Lehigh Valley Hospital in Hazleton, Pennsylvania, had Smith rushed to the hospital for care.

    "You're not dead until you're warm and dead," Coleman said on the Lehigh Valley Health Network website -- referring to a phenomenon in which people who are kept at cold temperatures can be revived despite a lack of vital signs.

    When Smith was brought into the emergency room, Coleman couldn't even get an accurate body temperature reading because Smith was too cold. But the doctor did not give up. He transferred Smith via helicopter to a hospital where he could be hooked up to a machine called an ECMO (extracorporeal membrane oxygenation), which warms the blood and oxygenates it then pumps it back into the body.

    Dr. James Wu, a cardiothoracic surgeon at Leigh Valley Hospital at Cedar Crest, said it was a still a long shot that Smith could survive but after the machine was turned on, within 90 minutes his heart was beating on his own.

    “With very low temperatures, it can preserve the brain and other organ functions," Wu said at a news conference on Monday.

    In spite of his nearly miraculous survival, Smith didn't wake up immediately. Doctors were concerned he could have had serious brain damage. He also had severe frost bite and lost his toes and pinkies due to frostbite.

    Approximately 30 days after he was found with no pulse, Smith woke up in a hospital room surrounded by family. He now is back at school at Penn State and aims to get a degree in psychology.

    "It’s amazing," Smith said at the news conference about his survival. "It’s something I never heard of and I can’t thank everyone enough.”
    ===========================================
    Smith spent nearly three months at LVH-Cedar Crest and at Good Shepherd Rehabilitation Hospital in Allentown before returning home May 1.
    ------------
    http://www.mcall.com/news/local/mc-mcadoo-man-brought-back-from-dead-20160118-story.html


    .
     
    Last edited: Jan 21, 2016
    seanb4 likes this.
  15. JanSz

    JanSz Gold

    https://www.facebook.com/groups/Quantlet.Registered.Users/permalink/1693554507552075/

    John Smithyou can be dehydrated due to a mold infection (CIRS). Once infected your α-MSH levels tank which effects ADH. No matter what you do you're screwed until the infect is handled. unsure emoticon
    "}" class="UFILikeLink">Like · Reply · 2 mins
    [​IMG]
    Jack Kruse
    Not true.......that is a meme brought on by DA and Shoemaker. I have a ton of moldy folks in NOLA and all get told about water and light and boom.........mold goes bye bye.
     
  16. JanSz

    JanSz Gold

    http://www.amazon.co.uk/Dermfix-300...d=1453463290&sr=8-2&keywords=Androv+3000+UV-B

    Dermfix 3000 UV-B Lamp for Vitamin D

    Product Description
    In response to customer demand we are pleased to offer our latest Androv 3000 desktop unit, fitted with narrowband UVB tubes for the production of Vitamin D3 (also called cholecalciferol). Vitamin D3 is naturally manufactured within the skin when 7-dehydrocholesterol reacts with UVB light at wavelengths between 270 and 315 nm. The tubes in this unit produce narrowband UVB primarily around the 310-312nm region to produce Vitamin D. This minimises the chances of skin redness or burning (erythema) which occurs more readily around the 290 to 305nm UV wavelengths. In the Northern Hemisphere between October and May the sun is low in the sky and the sun's rays are so well filtered by the atmosphere, that very little Vitamin D can be manufactured by the body. There is a great deal of research, easily accessed via the internet, into the side-effects of low Vitamin D levels in the human body, and associations with peripheral vascular disease, multiple sclerosis, high blood pressure, rheumatoid arthritis, Parkinson's disease, Alzheimer's disease and certain cancers.
     
    lilreddgirl likes this.
  17. lilreddgirl

    lilreddgirl New Member

    More expensive than the Sperti Vitamin D though... I wonder what band range Sperti uses... maybe it's time for a phonecall to the company... :)
     
  18. JanSz

    JanSz Gold

    Guy in Belgium just told me that between price and custom charges this one will cost him less.

    .
     
    lilreddgirl likes this.
  19. JanSz

    JanSz Gold

    https://www.facebook.com/groups/872967099382852/1131472340198992/

    @Jack Kruse
    The details matter...............now consider that the RPE has more DHA than any other tissue in humans.

    Consider your pic above............then consider this: In 2005, researchers at Wake Forest University School of Medicine found that two genes, ApoA4 and ApoE, help to determine the amount of docosahexaenoic acid (DHA) and total fat in the breast milk mothers produce.

    DHA is an omega-3 fat that is critical in the development of the brain and the RPE in the eye. DHA deficiency is believed to play a role in euro-degeneration, autism, attention deficit hyperactivity disorder, and learning disabilities. Mothers who carry the 347S variant of ApoA4 produce 40% more DHA in their breast milk than women with the more common (347T) version. 347S is more prominent away from the equator and 347T is present in equatorial humans.
    Attachment Unavailable
    This attachment may have been removed or the person who shared it may not have permission to share it with you.
    ------
    Jack Kruse
    Jack Kruse APOe4 is the key to the out of Africa migration.......and why homo lived and other species died off in Northern Europe..........if you cannot make enough energy further from the equator you suffer.........and the Neanderthals has 120 gems more brain tissues than us........might it have been they could not handle a low UV environment because of their larger brains? I think so.
    ====================================================



    http://www.spectracell.com/clinicians/products/apolipoprotein-e-genotyping/

    Apolipoprotein E Genotyping
    Overview

    This test determines an individual’s genetic risk associated with the Apolipoprotein E gene. ApoE is involved in the metabolism of cholesterol and triglycerides, and variants in this gene can have clinically relevant implications for disease risk as well as one’s response to statin therapy, dietary fat, and other risk factors (eg., smoking and alcohol consumption). Approximately 45% of individuals carry one or more of the high risk variants within the ApoE gene. The results of the genotyping of Apolipoprotein E have important implications in the treatment strategies for individual patients in reducing cardiovascular disease risk.
    Components


    [​IMG]

    [​IMG]



    I have tested, it is E3/E3.


    ''
     
  20. lilreddgirl

    lilreddgirl New Member

    I feel concerned... this study shows levels of D over 89 correlated with heart disease... these levels are presumably through natural sun exposure too :(

    http://www.ncbi.nlm.nih.gov/pubmed/11949730?dopt=AbstractPlus

    make sure to up the K2 if you don't trust your (lower) gut? to make adequate amts while ramping up D lamp use...

    ---------

    other reason I am freaked out re D is that I read quite a few articles suggesting pathogens lower ability of 1.25 D to act on VDR receptor resulting in low 25D (the measured one) and HIGH 1.25D.

    curcumin may (or may not) help with this 'VDR dysregulation' problem

    In this case upping the D might even not be beneficial, lowering inflammation and symptoms but not eradicating underlying infection. Am hoping that perhaps raising D extra extra high above 100 might override this problem...
     
    Last edited: Jan 27, 2016
    seanb4 likes this.

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