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Low Cortisol Levels

Discussion in 'Optimal Labs' started by Eddie Garza, Apr 29, 2015.

  1. DrEttinger

    DrEttinger Choice, the only thing we control

    Basic physiology states that any form of stress on a cell will make the cell use-up its potassium faster, which means the demand for it increases.
     
    John Schumacher, JanSz and Inger like this.
  2. JanSz

    JanSz Gold

  3. Penny

    Penny New Member

    I just go to the fish store and get a 4oz bottle for $6.00 - my son has done MB by the dropper full - and he's still here - my husband a couple years back had some diarhea/puking flu and as I watched him suffer needlessly I said "Ya know, MB was originally invented to cure malaria" him:"Well, if it'll make you feel better" (typical man...) 2 hours later after 1 drop in some ice water he stops puking and crapping - 5 hours later he tells me "I'm going to get on the exercise bike and clean the rest of it out" to which I yelled at him "your mitochondria are already *shit*, and do not need any more stress!" Thanks Dr. Ettinger for any dosing recommendations - they are truly difficult to come by:) I've read your stuff off and on for years:)
     
    DrEttinger likes this.
  4. Penny

    Penny New Member

    If Covid-19 is causing acute hypokalemia then I would not be surprised if its also causing pyruvate dehydrogensase (PDH) to decline in the mitochondrial TCA cycle. There are reports of those who recover from the virusare getting out of breath more easily which possibly implies
    a) inappropriate Cori activation due to pyruvate dehydrogenase and thiamine deficiency leading to lactic acidosis and depletion of alkalizing buffers in our blood .
    b)It also implies acute drops of NAD+ levels at cytochrome one. This also would explain kidney failure and severe respiratory failure associated with Covid-1.

    THE BLACK SWAN MITOCHONDRIAC TAKE:
    Potassium levels tell us about the relationships to cellular ATP made by mitochondria. In this way, they are like CO2 and water levels in cells because mitochondrial ox/phos makes CO2 and water as their normal exhaust products since the reverse photosynthesis. K+ stoichiometry: For every 0.3 mEq below 3.8 mEq that potassium is on a standard blood lab draw, means there is 100 mEq deficit inside a cell. The atomic size and its redox potential is huge for potassium “gluing of water” for it to function as the optimal electrical adapter to transfer energy throughout the cell coherently. ATP is designed to unfold proteins fully to open their carbonyl and imino side chain groups on all amino acids to intracellular water. This action allows binding and polarization to separate water into subatomic particles that are positively and negatively charged. This action is called building or expanding the exclusion zone (EZ) of water.
    Expanding the exclusion zone allows water to form polarized layers around the hydrophilic proteins, and the earth’s magnetic field then orients these polarized liquid crystals by a principle called “spintronics.” Controlling the electron spin at a right angle to the direction of flow of electrons allows for the formation of massive super conducting proton cables all over your body. This is why sleeping on a magnetic pad at certain times might be a smart move when you understand the context of your redox potential.
    “Spintronics” was described in the February 2014 webinar for members. This gives you alternating positive and negative magnetic dipoles of water molecules that have their electrons locked in at 90 degree angles to the current of flow around these proteins. In this way, the magnetic field can control the action of water and collagen where they meet, both inside and outside of cells. Gilbert Ling found that the orientation of positive to negative water molecule binding was 3.1 Angstroms apart when theses conditions are met.
    You must pay attention to your Potassium (K+) levels. The reason potassium is critical inside a cell, and supersedes magnesium and sodium ion concentration is because it is naturally tied to beta and gamma carboxyl side chain groups found in proteins, where potassium specifically binds because of “quantum advantages.” These beta and gamma carboxyl bonds allows K+ to ADSORB to this protein site and donate electrons (this is why K+ has the second highest redox potential to Lithium in life; to the polarized water gel crystal.
    Each molecule of ATP in a cell controls 8,800 water molecule binding sites and 20 potassium ions to make this liquid crystalline semiconductor inside every cell of your body. Potassium acts like “the glue” to keep your protein back bone and water in a gel state inside your cell to maintain the semiconducting plates together in a cohesive form. This is why K+ is critical in setting the redox potential of water in a cell. In this way, you are building a special type of semiconductor that forms “the fourth phase of matter” and can act like a “topologic insulator.”(TI) A ‘TI’ allows quantum effects to happen in warm wet environments.
    https://www.thailandmedical.news/…/covid-19-research-update…
     
    Dio Tortorello likes this.
  5. JanSz

    JanSz Gold

    upload_2020-3-17_17-5-59.png


    -----------
    THE SAFIRE PROJECT has become a commercial venture. Based on the discoveries of the last six years, the SAFIRE team is currently developing a nuclear-plasma reactor which will have the capacity to both generate electrical power and to remediate radioactive waste.

    able to use radioactive nuclear spent fuel
    neutralizing nuclear radioactivity

    ..
     
    Last edited: Mar 17, 2020
    John Schumacher likes this.
  6. JanSz

    JanSz Gold

  7. JanSz

    JanSz Gold

  8. JanSz

    JanSz Gold

  9. JanSz

    JanSz Gold

  10. JanSz

    JanSz Gold

  11. JanSz

    JanSz Gold

  12. JanSz

    JanSz Gold

  13. JanSz

    JanSz Gold

  14. JanSz

    JanSz Gold

  15. JanSz

    JanSz Gold

  16. JanSz

    JanSz Gold

    www.covid19.nj.gov
    =================================
    *NEWS RELEASE* Six Parsippany-Troy Hills Residents Presumptively Test Positive for COVID-19

    Residents of Parsippany-Troy Hills,

    Today, I was informed by our Health Department that six Parsippany residents have presumptively tested positive for COVID-19. I am able to provide the following information, and only this information, on these cases at this time:

    - An 85-year-old female currently recovering at the hospital.
    - A 64-year-old female currently recovering at the hospital.
    - A 50-year-old male currently recovering at the hospital.
    - A 47-year-old female currently quarantined at home.
    - A 40-year-old female currently quarantined at home.
    - A 34-year-old male currently quarantined at home.

    I want to emphasize that our first presumptive positive tests were inevitable. Continuing to follow the advice of public health officials is still the best deterrent to the spread of this virus to you, your loved ones, and the community as a whole. Hand washing, disinfecting of surfaces, social distancing, and related recommendations must continue to be implemented by all residents.

    Personal and collective vigilance is our best chance at minimizing the risk of this virus.

    My administration remains in constant contact with our state and county partners, and we will release additional information as it is provided.

    Please remember to consult your personal doctor if you exhibit any symptoms of illness. The Township will continue to provide accurate and up-to-date information as quickly as possible. The State of New Jersey has set up a comprehensive website covering many questions you may have regarding COVID-19, as well as a telephone hotline. For more information, please visit www.covid19.nj.gov or call 211.

    Michael Soriano
    Mayor

    covid19.nj.gov
    www.covid19.nj.gov
     
  17. JanSz

    JanSz Gold

    Last edited: Mar 23, 2020
  18. JanSz

    JanSz Gold



    Special Feature: HOW STARS ARE FORMED
    6,224 views
    •Mar 21, 2020
     
  19. JanSz

    JanSz Gold

    https://www.discovermagazine.com/health/what-the-coronavirus-does-to-the-body

    What the Coronavirus Does to the Body

    Here’s what experts know about how the new virus hijacks cells and damages organs like our lungs.
    By Alex OrlandoMarch 20, 2020 3:35 PM
    [​IMG]
    (Credit: Andrii Vodolazhskyi/Shutterstock.com)
    Newsletter
    Sign up for our email newsletter for the latest science news

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    As the novel coronavirus infection known as COVID-19 continues to spread across the world — the number of confirmed cases in the U.S. crossed 15,000 on Friday — governments have made incredible efforts to limit the pandemic’s overall reach.

    Yet there is also much uncertainty, and a fair amount of unscientific speculation, about the virus and its effects on people’s bodies. And some of COVID-19’s reported symptoms, like fever, cough and shortness of breath, overlap with those of everyday illnesses like strep throat, flu and the common cold.

    Carl Fichtenbaum, an infectious disease specialist and professor of clinical medicine at the University of Cincinnati College of Medicine, says there’s still much that scientists don’t understand about how exactly this virus causes problems. “It’s very new, and we’re still trying to unravel it a little bit,” he says.

    Here’s what some researchers and clinicians have learned so far about what the COVID-19 infection does to the body.

    How the Coronavirus Causes Infection
    The virus that causes COVID-19 is transmitted through tiny, invisible droplets sent into the air when someone already infected coughs or sneezes. Those droplets can then be taken in by people nearby or land on surfaces that others touch, potentially passing viral particles from their hands to their eyes, nose or mouth. “Generally, a person will either get it on their hands or occasionally inhale it in their mouth or nose,” says Fichtenbaum.

    Once inhaled into the back of your throat and nasal passages, the viral particles bind to a type of receptor on the surface of cells. These particles are studded with jagged proteins shaped like spikes, which Fichtenbaum describes as a key capable of opening the locked door of the cell receptor. “Those proteins attach to the receptors and the virus is able to begin the process of getting inside and replicating,” says Fichtenbaum.

    “Like any other life form, it just wants to survive,” he says.

    In order to do that, the virus needs to first copy itself. Once attached to cells, it spills its genetic material, or RNA, inside. Afterward, the virus takes over the cell’s metabolism to create “replication factories” to make more copies of its RNA. “It’s essentially stealing resources from the host cell,” says Robert Kirchdoerfer, a biochemist at the University of Wisconsin-Madison who studies coronaviruses.

    What it Does to the Lungs
    As the virus multiplies, it prompts an immune response in the body. “[The immune system] says, ‘We don’t like this thing and we want to get rid of it,’ ” says Fichtenbaum. Once that battle occurs, he continues, people start to develop symptoms as previously healthy tissue becomes damaged and inflamed. These symptoms include a sore throat, runny nose, sneezing, coughing and, sometimes, fever. “If the virus passes low enough and gets into our lungs, we can develop pneumonia, which leads to shortness of breath and chest pain,” adds Fichtenbaum.

    For the bulk of the population, explains Fichtenbaum, this period of injury will be followed by a recovery period. “Most people will get better from it,” he says. At the same time, the Centers for Disease Control and Prevention cautions that older adults and those with serious, preexisting medical conditions — like heart disease, diabetes and lung disease — are at greater risk of becoming severely ill if they become infected.

    “That’s not to say that everyone with those problems is going to have a bad time,” adds Fichtenbaum. “It’s just that they’re more likely than an otherwise healthy person to have a worse case.”

    Other Parts of the Body
    The lungs aren’t the only part of the body that can be affected by the virus. Fichtenbaum says that in some people, the infection can cause the heart to beat at irregular intervals and pump less powerfully, potentially leading to heart failure. “Sometimes people can have neurologic problems [like] dizziness or weakness in an arm or a leg,” he says. “And some confusion can occur because our brain is just not functioning as well as it should be.”

    Because the virus can be swallowed, it can also infect cells in our gut. Since the outbreak of the virus last December, digestive problems have been a common complaint among those infected. The CDC reported that genetic material from the virus has been found in blood and stool samples.

    And new research suggests that diarrhea and other gastrointestinal problems could be among COVID-19’s first signs. According to a study published Thursday in the American Journal of Gastroenterology, nearly half of the coronavirus patients involved came to the hospital with “digestive symptoms as their chief complaint.” The study authors looked at data from 204 patients in China’s Hubei province, where the outbreak originated, and found that 99 of them had symptoms such as diarrhea, vomiting and abdominal pain.

    But these are still early days for research on this new coronavirus. “There’s still things for us to learn,” says Fichtenbaum. “And, of course, we’d like to understand and learn how to treat it when it is like a more serious case.”
     
  20. JanSz

    JanSz Gold

    https://www.straightdope.com/columns/read/1342/will-the-quinine-in-tonic-water-prevent-malaria/

    Will the quinine in tonic water prevent malaria?


    August 13, 1999


    Dear Cecil:

    Tonic water contains quinine, because (I gather) quinine was the "tonic" against malaria in Britain's colony days. So is the dose in tonic water today the same as it was when it was being used medicinally? If so, does drinking tonic water today actually affect my chances of getting malaria? If not, why do soft drink companies keep putting it in?

    Toph, via the Internet

    [​IMG]
    Illustration by Slug Signorino

    Cecil replies:

    I can see where you’re going with this. You’re tossing back that fourth gin and tonic and thinking, Man, I’m really marinating the old hypothalamus here. But at least I won’t get malaria.

    Nice try, sport, but no dice. Tonic water contains less than 20 milligrams of quinine per six fluid ounces. The recommended quinine dosage for treatment of malaria is two or three 200-350 milligram tablets three times a day. If you drink the equivalent of that in gin and tonics, malaria will be the least of your problems.

    Tonic water was never intended as a cure or preventive for malaria, but malaria is the reason the quinine is in there. Quinine has a bitter taste. To make the stuff palatable when used as an antidote for fevers, legend has it, British colonials in India mixed quinine with gin and lemon or lime. Over time they learned to love the godawful stuff. (You can see this principle at work in a lot of British cuisine.) Tonic water was granted an English patent in 1858, Schweppes brought it to the United States in 1953, and to this day it remains an essential component of Anglo-American mixology. Quinine is also used, along with other herbs, to flavor vermouth.

    It’s only fitting that we toast quinine (well, toast with quinine). Few drugs have been such a boon to humanity. Quinine comes from the bark of the cinchona tree, which grows in the rain forest on the eastern slopes of the Andes. (One begins to comprehend the importance of preserving rain forests.) The Spanish first heard about the medicinal properties of the bark of the “fever tree” from the natives in the early 17th century. According to tradition, the stuff was used in 1638 to cure Countess Anna del Chinchon, wife of the viceroy of Peru, an event commemorated a century later when botanists named the plant. The viceroy shipped a boatload of it to Europe in 1640, and the Jesuits began using it in their missionary work, whence it acquired the nickname “Jesuit’s powder.” For a time religious and national rivalries kept quinine from being universally adopted, but eventually everybody began using it, and many historians today say it permitted the European conquest of the tropics.

    Quinine was the only effective treatment for malaria for 300 years. After World War II, however, it was largely supplanted by synthetic drugs such as chloroquine that were safer, more effective, and easier to make. (Though quinine kills malarial parasites in red blood cells and alleviates fever, it doesn’t completely destroy malaria in the body, allowing relapses to occur if quinine therapy is halted.) But some strains of the malarial parasite Plasmodium falciparum became resistant to the synthetic drugs — one reason the global malaria eradication program launched by the World Health Organization in 1955 was declared a failure in 1976 — and in some parts of the world quinine has again become the antimalarial drug of choice.

    One last thing. (I know we’re getting off the track of tonic water, but when else am I going to get a chance to use this stuff?) Schweppes claims to have invented the soft-drink business by patenting a process for carbonating water in 1783. The hard part was keeping the carbonation from seeping out of the bottle when the cork dried out. Schweppes’s solution was classic: to ensure that the corks stayed damp, the company used bottles with rounded ends so they couldn’t stand upright. Drink enough gin and tonics, and neither will you.

    Cecil Adams
     

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