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Interesting Study - Confirms what we already know!

Discussion in 'The New Monster Thread' started by Jim, Jul 31, 2012.

  1. Jim

    Jim New Member

    Interesting study that confirms what we already know!



    Mice lacking δ-opioid receptors resist the development of diet-induced obesity



    Abstract



    Pharmacological manipulation of opioid receptors alters feeding behavior. However, the individual contributions of each opioid receptor subtype on energy balance remain largely unknown. Herein, we investigated whether genetic disruption of the δ-opioid receptor (DOR) also controls energy homeostasis. Mice lacking DOR and wild-type mice were fed with standard diet and high-energy diet (HED). Mice were analyzed in vivo with the indirect calorimetry system, and tissues were analyzed by real-time PCR and Western blot analysis. DOR-knockout (KO) mice gained less weight (P
     

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