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Heat stress, Heat shock proteins & Mitochondria news again...

Discussion in 'Mitochondrial Rx' started by Scompy, Nov 22, 2018.

  1. Scompy

    Scompy Gold

    More about heat-shock proteins and heat stress with the mitochondria...

    "Defects that occur in the biogenesis or function of the mitochondria can cause serious neurological or cardiovascular disease. To maintain proper function, mitochondria rely on around 1,000 different proteins that are imported from the cellular fluid or cytosol.

    Ribosomes within the cytosol not only produce proteins for the mitochondria but also precursor proteins, which are escorted from the ribosomes to the mitochondria by chaperone proteins. Since the interior components of these chaperones increases in response to heat stress, these molecules are also referred to as heat shock proteins (Hsps). One Hsps called Hsp70 is particularly important for carrying the precursors into mitochondria."

    Allin and Lahelada like this.

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