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Fever during pregnancy more than doubles the risk of autism or developmental delay in

Discussion in 'Optimal Kids' started by chocolate, May 28, 2012.

  1. chocolate

    chocolate Silver


    A team of UC Davis researchers has found that mothers who had fevers during their pregnancies were more than twice as likely to have a child with autism or developmental delay than were mothers who did not have a fever or who took medication to counter its effect.

    “Our study provides strong evidence that controlling fevers while pregnant may be effective in modifying the risk of having a child with autism or developmental delay,†said Ousseny Zerbo, lead author of the study, who was a Ph.D. candidate with UC Davis when the study was conducted and is now a postdoctoral researcher with the Kaiser Permanente Northern California Division of Research. “We recommend that pregnant women who develop fever take anti-pyretic medications and seek medical attention if their fever persists.â€

    Published online in the Journal of Autism and Developmental Disorders, the study is believed to be the first to consider how fever from any cause, including the flu, and its treatment during pregnancy could affect the likelihood of having a child with autism or developmental delay.

    The results are based on data from a large, case-control investigation known as the Childhood Autism Risk from Genetics and the Environment (CHARGE) Study. Another recent study based on CHARGE data found that mothers who were obese or diabetic had a higher likelihood of having children with autism.

    Irva Hertz-Picciotto, a professor of public health sciences at UC Davis and principal investigator of CHARGE, pointed out that fever is produced by acute inflammation — the short-term, natural immune system reaction to infection or injury — and that chronic inflammation, which no longer serves a beneficial purpose and can damage healthy tissue, may be present in mothers with metabolic abnormalities like diabetes and obesity.

    “Since an inflammatory state in the body accompanies obesity and diabetes as well as fever,†said Hertz-Picciotto, “the natural question is: Could inflammatory factors play a role in autism?â€

    She explained that when people are infected by bacteria or viruses, the body generally reacts by mounting a healing response that involves the release of pro-inflammatory cytokines from white blood cells into the bloodstream. Some cytokines are able to cross the placenta, and therefore could reach the fetal central nervous system, potentially altering levels of neurotransmitters and brain development.
  2. BeingVenus

    BeingVenus New Member

    Speaking out of left field but perhaps in addition to an inflammatory state this has to do with Fat soluable vitamin levels as well. For the past 20 years women have been told to slather on sunscreen at every oppurtunity. It's stuck in out moisturizers, our makeup. Fever and illness uses up much needed stores and if you aren't actively consuming large amounts of those activators to replenish them, they'll never be recuperated for the rest of the pregnancy. Also, people with low D levels tend to get sick more often in general.

    Anyway, I have nothing to back up my argument, though two years ago short birth intervals were associated with a LARGE increase in autism and short birth intervals = low nutrient stores as well. (unless you're again, actively and consciously replenishing them.)

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