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Brown Adipose Tissue

Discussion in 'Cold Thermogenesis' started by AKMan, Mar 14, 2012.

  1. AKMan

    AKMan New Member

    BAT is the holy grail for CT. It is activated by cold, when present, and increases the metabolism by turning energy stores into heat, bypassing normal cellular ATP functions.

    BAT is mentioned a lot in the Quilt and the CT series. It seems there are conflicting viewpoints on who has BAT. All babies have it, but it disappears as we age. Some studies suggest everyone still has a stockpile of BAT and that cold can regenerate it and even recruit new BAT from WAT. It seems to be accepted that obese people all have less BAT than thin people.

    What I'm wondering, and I've never seen a study on this, when obese people lose weight, do they end up with a normal amount of BAT or are they always deficient? Also, is there a way to assess if you have BAT and how much?
  2. David

    David Silver

    I read an article on line recently: "Brown Fat, Triggered by Cold or Exercise, May Yield a Key to Weight Control, NYT 1/24/12

    I copied a part of it, that says:

    "… reports that brown fat can burn ordinary fat and that glucose is not a major source of fuel for these cells. When the cells run out of their own small repositories of fat, they suck fat out of the rest of the body.

    In the study, a number of men were kept chilled, but not to the point of shivering, which itself burns calories. Their metabolic rates increased by 80 percent, all from the actions of a few ounces of cells. The brown fat also kept its subjects warm. The more brown fat a man had, the colder he could get before he started to shiver. On average the brown fat burned about 250 calories over three hours. But there is another type of brown fat. It has been harder to study because it often is interspersed in the white fat and does not occur in large masses. Investigators discovered it years ago. A recent article reports that in mice exercise can make it appear by turning ordinary white fat brown. ... With exercise, mice muscle cells release a hormone that the researchers named irisin, which converts white fat cells into brown cells. Those brown fat cells burn extra calories. Irisin is induced with exercise in mice and humans..."

    I thought that looked quite promising.
  3. villjamur_stevenson

    villjamur_stevenson New Member

    I'd love to be able to recruit some more BAT from all of my WAT!
  4. ealachan

    ealachan New Member

    I've been wondering the exact same thing since reading all these articles about BAT and WAT and BRITE, etc.
  5. Jack Kruse

    Jack Kruse Administrator

  6. angie-s

    angie-s New Member

    How can we reduce the two phosphate enzymes in POMC, as mentioned in the article, to promote the sensitivity of Leptin and insulin and increase BAT. Will some kind of supplements help ?
  7. CTforlife

    CTforlife New Member

  8. Penny

    Penny New Member

    bitter melon - or just juice the fruit - you can find it at Indian stores... take one after you eat a carb...

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