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berberine as a metformin alternative?

Discussion in 'Adrenal Rx and Leaky Gut Rx' started by chocolate, May 13, 2012.

  1. chocolate

    chocolate Silver

    http://www.naturalmedicinejournal.com/article_content.asp?article=61

    Friday, October 01, 2010

    by: By Ronald Steriti, ND, PhD

    Section: Peer-Reviewed Articles



    About the Author



    Ronald Steriti, ND, is a researcher for Dr.

    Jonathan V. Wright, director of the Tahoma

    Clinic and Meridian Valley Labs. Steriti is a

    graduate of the Southwest College of Naturopathic

    Medicine.

    Abstract

    This brief review focuses on several studies that show the plant alkaloid berberine can lower

    blood glucose as effectively as the drug metformin at similar doses (500 mg 3x/day). Berberine

    acts on glucose metabolism through several mechanisms, including (AMP-activated protein

    kinase) AMPK and incretins.
     
  2. chocolate

    chocolate Silver

    http://www.nature.com/ncomms/journal/v3/n5/full/ncomms1859.html



    Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC


    I didn't search to compare the pathways of metformine and berberine.
     
  3. chocolate

    chocolate Silver

    http://www.ncbi.nlm.nih.gov/pubmed/21422199




    I hadn't heard about this study.
     
  4. chocolate

    chocolate Silver

    http://www.ncbi.nlm.nih.gov/pubmed/22574158


    or this one
     
  5. KiwiLauren

    KiwiLauren Gold

    I had read some of those, too, Chocolate... as well as studies showing berberine had equal results as metformin re: BG, but even better results in other measurement domains. Looks to me like both are very good. Since metformin is a pharmaceutical product, it will get much more research behind it.
     

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