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Discussion in 'The Epi-Paleo Diet' started by Jack Kruse, Dec 9, 2019.

  1. Jack Kruse

    Jack Kruse Administrator

  2. JanSz

    JanSz Gold

    Circadian rhythm is always #1
    If you do not measure it will not get fixed.

    High insulin=Leptin resistance.

    Do not measure leptin.
    Do measure insulin.
    Get the chart.

    Anything above blue line =leptin resistance=too high insulin=insulin resistance=metabolic syndrome
    Insulin Fasting Blood Test
    Test #004333

    Insulin Response Blood Test, 3 Specimens
    Fatty Acid Profile, Comprehensive (C8-C26), Serum

    Make sure that those are individual fatty acids, results have upper and lover boundary.
    Avoid combinations, because there are forged tests with preconceived objectives (that are not health related).

    Last edited: Dec 10, 2019
  3. JanSz

    JanSz Gold

    What is on my mind.

    How to (practically) limit them in daily life?

    Juices concentrate (good and bad)
    structured (live) water, from low deuterium sources, must be good
    Dose makes poison

    I could use a list of foods that are low in deuterium and fructose, especially fruits (easily accessible, not exotic).
  4. Sue-UK

    Sue-UK New Member

    Perhaps seasonal rhythm should go to number 2. :) https://www.nytimes.com/1995/03/14/science/modern-life-suppresses-an-ancient-body-rhythm.html
    The gender differences are interesting.

    1995 was pre a lot of the current blue light/nnemf, but in terms of ancient body rhythms, a "dose" that might be neutral, or even beneficial, in one season, could be more problematic in another, or a "fake" season. For example a high animal fat diet in the winter when we are using it to generate heat to survive the environment has a different context to us living in the same latitude, but in houses heated to summer temperatures, and where we follow an artificial 16 hour summer day/night schedule. It being low deuterium may not be relevant.

    Even on a circadian basis, if we are more insulin sensitive in the early morning than we are in the evening, the same "dose" can have different effects, depending on when you ingest it. That seems to apply to fructose too.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078737/ Timing of Fructose Intake: An Important Regulator of Adiposity

    "It is important to know that not only is the amount of fructose intake important, but also the timing. In a test of intake rhythms, we found that fructose taken during the light, inactive phase in mice has pathological consequences. This is seen as enhanced adiposity and high leptin and insulin "

    As humans aren't nocturnal, it suggests that moderate daytime eating of seasonal fruit (whole, not mucked about with such as juices or smoothies, or cooked with added sugar) will not have the same pathological consequences as the same food being eaten after dark or eaten chronically out of season.
    Alex97232 and JanSz like this.
  5. shah78

    shah78 Gold

    i don't think i've eaten 100 calories after
    dark all 2019. quantum brady lives!!!:)
    Freebird, Alex97232 and Saichi like this.
  6. JanSz

    JanSz Gold

    More and more looks to me that every time @Jack Kruse says: leptin resistance
    I should be hearing
    high insulin=insulin resistance
    test it
    and when actually even slightly highish
    examine (again) what I eat.

    Unfortunately, the food industry is (secretly) feeding us with sugar.
    They invented 50 names for sugar
    The law is written in a way that they do not have to post sugar content on labels.

    50% of sugar is fructose which does the real damage.

    Alex97232 likes this.
  7. Jack Kruse

    Jack Kruse Administrator

    Food is just data on sunlight’s photonic power that it packs into food as it travels around our star. So can food hurt us if we do not have enough electrons in our cell membranes or mitochondria? Yes. Why? Highly powered electrons (carbs) can short out our cell membranes if they have no charge (delta Psi) in them. Charge is built best by UV/IR light via the surfaces of the body, like the eye and skin. We need to assimilate it. We need an adequate balanced diet of light in the game of life to deal with food electrons with high power…………….Jablonski diagram no matter how you dress up the marketing. Life is all about proteins capturing the light that excites that electron as it falls back to the ground state.
    That light in food is carried on the back of electrons, and the said electrons in food are delivered to your mitochondria for quantum processing. Their power has to match the power signaled via the eye and skin surfaces. What if it is not? You get an electrically shorted out system (low redox state) at these surfaces to cause more ROS than is normal and this results in some disease.
    This is why I never focus on food. I focus on my light environment to make food obsolete in the equation of life. Don’t try to let food or exercise be the missing key in your life, or light will stop being your unmatched lock and key mechanism that leads to disease; Food answers little for the sick because the photonic power’s absence or presence must be yoked in your eye, skin, and gut. If it does not that doesn’t let you merge on the path to optimal and eventually, you’ll leak so much light from cells (ELF-UV) that illness is the ultimate result. The results were not weird........you just missed the uncontrolled light variables.
  8. JanSz

    JanSz Gold

    Kevin Pope and Karen & Glen C. like this.
  9. Jack Kruse

    Jack Kruse Administrator

    Alex97232, JanSz and Brent Patrick like this.
  10. Jack Kruse

    Jack Kruse Administrator

    I thought paleo keto helped metabolic diseases like cancer?

    Paleo/keto food guru with stage 4 lung cancer. I guess food and exercise are not all that she and Robb Wolf crack it up to be. Robb Wolf, the author of The Paleo Solution and Wired to Eat, is a former research biochemist who pushed Hallberg to media prominence when I gave the original keynote at PaleoFx in 2011. She was called a ground breaking physician at the time by Wolf because of her ideas around low carb keto diets.
    People you have to be careful who packs your parachute. She has been low carb and paleo/keto for over a decade and yet she still got a mitochondrial disease that Rx of food couldn't cure. Food might be medicine but it is not medicine for a disease linked to aberrant light exposure at night and high latitude living during the day.
    She lives in Lafayette, Indiana which was one of the first cities to adopt 5G in the USA. She also works for keto warehouse guru maker Virta health.
    Here is her Rx below
    Did it work? Cancer is a disease of abnormal light radiations that alter the free radical signal in mitochondria and food and exercise cannot fix nor cure it. https://www.specialtyhealth.com/pdf...ant Insulin Resistance Thoughts 6.24.2016.pdf
    Brent Patrick, Alex97232 and JanSz like this.
  11. Jack Kruse

    Jack Kruse Administrator

  12. Jack Kruse

    Jack Kruse Administrator

    Can sitting in artificial blue light day or night or wearing sunglasses, contacts or glasses or the use of sunscreen lead to changes in NO pulses and diseases like cancer?

    It turns out nitric oxide produced in and around the head and neck blood supply is transmitted to the various vagal nerve branches to travel toward the brain and down into the gut. The vagus concerns itself with things that cool these surfaces but make sure the pH is perfect to build a large exclusion zone in water in the cells below that particular tissue surface. This temperature variation acts to make sure the local mitochondrial ATPase (5th cytochrome) spins as fast as it can because the red light that builds the EZ in water can be used to rotate the ATPase to make it a 100% efficient quantum nano rotatory engine. The vagus nerve connects the entire gut down to the transverse mesocolon of the hindgut to the fourth ventricle of the brainstem. This 4th ventricle is filled with CSF (99.8% water) and the vagus nerve is covered with myelin in connection with this CSF. Cooler surfaces have more electron density in their cell water. Since light only interacts with electrons in nature, this makes cooler water more likely to interact with solar light. This becomes the MOST important balancing stimulus to improve the fidelity of the ANS signals for cells in the body.


    The vagus nerve includes axons which emerge from or converge onto four nuclei of the brainstem in the medulla:

    1. The dorsal nucleus of the vagus nerve — which sends parasympathetic output, which is the secretomotor parasympathetic nucleus. Secretomotor primarily means that it stimulates glands - including mucous glands of the pharynx, lungs, and gut, as well as gastric glands in the stomach.
    2. The nucleus ambiguus — which gives rise to the branchial efferent motor fibers of the vagus nerve and preganglionic parasympathetic neurons that innervate the heart
    3. The solitary nucleus — The solitary nucleus receives taste information, the sensation from the back of the throat, and also visceral sensation. Visceral sensation includes blood pressure receptors, blood-oxygen receptors, sensation in the larynx and trachea, and stretch receptors in the gut. The eye has a UV-A light opsin that stimulates nitric oxide (NO) release in the eye and in the nasal passages using the 5th cranial nerve. The 5th nerve releases the NO to the blood plasma and this stimulates the vagus receptors in the circulatory system to alter blood flow to the brain. This is how the nitric oxide release occurs from the light stimulus of the neuropsin receptor of the eye that innervates the first two divisions of the trigeminal nerve that innervates the sinuses connects to the vagus nerve at the superior cervical ganglion and circulatory system.
    4. The spinal trigeminal nucleus — which receives information about deep/crude touch, pain, and temperature of the outer ear, the dura of the posterior cranial fossa and the mucosa of the larynx.
    The stimulus of light changes CSF in the brain and in the gut. This is how the “central digital” circadian system from the RPE of the eye is linked to the SCN which sits in a cistern of CSF above your optic nerves in your skull. The “analog circadian system” of the gut is linked to light exposure from food electrons and to the timing of food grown in the environment that cells get in our mitochondria so that the signals can be yoked via the area postrema (AP) and the median eminence (ME) in the brain. These two areas of the brain have no blood-brain barrier. They allow water and light communication to occur, so the electron density in the CSF is accurately tied to the local environment these neurons can sense. Electron density and coolness are linked in water. This is true in the ocean and in our cells and CSF cavities. For example, when we eat, 60% of blood flow is shunted from the peripheral blood to the gut’s mesenteric system by the autonomic nervous system. The brain senses and pays attention to these shifts, using the vagus nerve, as its main information highway. When the sun hits our skin, nitric acid (NO) is released and 40-60% of blood flow raises to the skin surface to become radiated by solar radiation. This energy transfer is sensed by the vagus nerve at our superior cervical ganglion and sent to the brain to lower our stress response in the PVN. So if your lifestyle buries the sun, you create a stress response and if you do it long enough you might end up with a disease like cancer.
  13. Green Eyes

    Green Eyes Silver

    Boy another reason to love Summer
    caroline likes this.
  14. Jack Kruse

    Jack Kruse Administrator

    Why was the Epi-Paleo Rx written? Because over 1000 papers link DHA to optimized health. This is now the 17th metanalysis to back up my intuition that if you want to be healthy you need DHA electrons to capture all that sunlight. That is the photoelectric effect 101 wisdom at work. This is a study of association, but well-conducted, and robust data that confirms over 1000 other studies on DHA. The findings inside this paper suggest that higher circulating levels of marine n-3 PUFA are associated with a lower risk of premature death. DHA has not been replaced one time in 650 million years of evolution on Earth. That record should tell you something but even today we have ignorant people telling you seafood should be avoided. We have to stop making these ignorant people famous.

    The smallest or seemingly least important of things must be done because everything in the Universe is connected. Each step leads to the next step, and so forth and so on. Someone must do the initial work to get a job done. Neither the first step nor the last are of greater significance. They are both needed to accomplish the task. Past, Present, and Future are all connected.

    Imagine that. 16 years and running I have been saying.........are you listening? https://www.nature.com/articles/s41467-021-22370-2
  15. Over the years, this is the gift people get from me -> "Epi-Paleo Rx" by Dr. @Jack Kruse
  16. JanSz

    JanSz Gold

    average density of Sun's irradiance at the top Earth's atmosphere on an imaginary surface
    perpendicular to the sunlight rays and it's value is approximately 1366 watt per square meter
    an average amount of sunlight received at
    the Earth surface per square meter is 341×0.48=163 W/sq.m, or 15 watt per square foot.
    As food, we get 3000 calories (say) ---->>3000 cal = 3.489 Wh=0.003489 Kwh
    each person at rest synthesizes water that gives 32500 kW over 24hr day, 3x that much when working
    That is a tremendous amount. All else is less than a really small fraction of 1% of that number.
    Above we should look at proportions (we do not).

    When I drive a car I am interested in how much energy it works with to drive from A to B.
    I am rarely interested in how much energy that car uses for closing the window or run windshield vipers.


    From what is written on the picture below, it looks like we are making energy on both sides of the cycle.
    so the 32500 kW may be just a half of the story.
    Last edited: Apr 27, 2021
  17. Thank you Dr. @Jack Kruse for the reference. If you don't mind, may I brief the article -> Higher fish intake seems good for you.

    Its benefits (these LC n-3 PUFAs not ALA) are hypotriglyceridemic, antihypertensive, and antiplatelet effects; as well as positive effects on adipocyte biology, endothelial function, and autonomic balance. All of these appear to be mediated by effects on membrane physiochemistry, gene expression, and the production of a myriad of bioactive oxylipins. These fatty acids have been reported to inhibit the mammalian (or mechanistic) target of rapamycin (mTOR) in animal studies showing benefits in cancer, metabolic syndrome, spinal cord injury, and depression. mTOR inhibition extends lifespan in many species and acts as an energy sensor to coordinate gene expression, ribosome biogenesis, and mitochondrial metabolism.


  18. Danco3636

    Danco3636 Silver

    YEP... I follow the book still to date....... Keeps me young, strong and full of life......
    Freebird and John Schumacher like this.
  19. Jack Kruse

    Jack Kruse Administrator

    God said, let there be light, so optics was born. Einstein replied, “let it be quantized”, then photonics was born. Photonics over electronics is an ancient meme modern humans have ignored. Human technology abrogates the wisdom of nature. The result is seen in modern human diseases. We’ve gone from the stone age to the iron age, and are now firmly in the electronic age but that age is coming to an end because we are hitting its physical limits in cells. This might be mankind’s best news regarding 5G. Photonics holds huge promise because it has unlimited potential because light is able to carry energy and information without being encumbered by mass. This unique ability shrinks circuits, currents, and voltages while increasing communication and signaling transmission speeds while lowering non-native EMF emissions. Now we have to get hospitals to understand why people in ICUs get more ill in ICUs at night when everything is lit up and plugged in. It occurs because of the electromagnetic radiation they receive during care at night and a lack of sun exposure during the daytime. I’m happy to say my new job is listening to me. We are planning on studying this soon in Florida. It also means the ICU lighting could make modern diseases' progression worse. Think about the current events around the most common disease in newspapers today = COVID. https://www.chronobiology.com/circadian-lighting-improves-patient-outcomes-icu/
    JanSz and John Schumacher like this.

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